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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK5
All Species:
13.64
Human Site:
S527
Identified Species:
23.08
UniProt:
Q3MIX3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MIX3
NP_777582.3
580
65897
S527
Y
R
G
V
Y
G
T
S
L
L
R
H
A
K
V
Chimpanzee
Pan troglodytes
XP_001157317
580
65781
S527
Y
R
G
V
Y
G
T
S
L
L
R
H
A
K
V
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
C461
F
L
N
M
S
R
C
C
I
R
A
L
A
E
H
Dog
Lupus familis
XP_539216
624
71219
S571
Y
Q
N
I
Y
G
A
S
L
L
R
H
I
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80V03
582
66636
S527
Y
Q
G
I
Y
G
S
S
L
L
R
H
I
K
V
Rat
Rattus norvegicus
NP_001129270
582
66734
R527
Y
Q
G
I
Y
S
S
R
L
L
R
H
I
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507044
482
54419
L436
D
G
Q
A
E
L
V
L
L
D
H
G
L
Y
Q
Chicken
Gallus gallus
Q5ZMT7
519
59182
C458
F
L
N
M
S
R
C
C
I
R
A
V
S
T
Y
Frog
Xenopus laevis
Q6INL7
520
59525
A464
M
S
R
C
C
V
R
A
L
A
R
H
R
K
E
Zebra Danio
Brachydanio rerio
XP_001341554
579
66788
S527
I
R
L
F
S
R
L
S
V
F
R
W
V
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648446
557
64196
W502
S
P
V
Q
Y
I
R
W
L
S
G
R
I
Y
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181542
582
67255
L529
S
F
P
K
C
L
F
L
I
F
R
S
D
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
A491
I
G
K
V
S
S
Q
A
V
L
E
A
K
R
A
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
K510
I
M
T
Q
Y
C
A
K
T
V
Y
D
E
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
34.4
77
N.A.
80.5
79.3
N.A.
56.2
32.2
32.9
60.5
N.A.
38.9
N.A.
N.A.
41.4
Protein Similarity:
100
99.6
51.7
83.3
N.A.
89
88.1
N.A.
63.7
49.6
51.5
76.5
N.A.
57.2
N.A.
N.A.
60.4
P-Site Identity:
100
100
6.6
66.6
N.A.
73.3
60
N.A.
6.6
0
26.6
20
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
80
N.A.
93.3
80
N.A.
6.6
26.6
33.3
26.6
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.7
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
15
15
0
8
15
8
22
0
8
% A
% Cys:
0
0
0
8
15
8
15
15
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
8
0
8
8
8
% E
% Phe:
15
8
0
8
0
0
8
0
0
15
0
0
0
0
8
% F
% Gly:
0
15
29
0
0
29
0
0
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
43
0
0
8
% H
% Ile:
22
0
0
22
0
8
0
0
22
0
0
0
29
0
0
% I
% Lys:
0
0
8
8
0
0
0
8
0
0
0
0
8
50
0
% K
% Leu:
0
15
8
0
0
15
8
15
58
43
0
8
8
0
8
% L
% Met:
8
8
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
22
8
15
0
0
8
0
0
0
0
0
0
8
8
% Q
% Arg:
0
22
8
0
0
22
15
8
0
15
58
8
8
8
0
% R
% Ser:
15
8
0
0
29
15
15
36
0
8
0
8
8
0
8
% S
% Thr:
0
0
8
0
0
0
15
0
8
0
0
0
0
8
0
% T
% Val:
0
0
8
22
0
8
8
0
15
8
0
8
8
0
43
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% W
% Tyr:
36
0
0
0
50
0
0
0
0
0
8
0
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _