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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK5
All Species:
19.7
Human Site:
S444
Identified Species:
33.33
UniProt:
Q3MIX3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MIX3
NP_777582.3
580
65897
S444
R
L
G
Q
L
W
G
S
H
L
L
S
R
E
E
Chimpanzee
Pan troglodytes
XP_001157317
580
65781
S444
R
L
G
Q
L
W
G
S
H
L
L
S
R
E
E
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
C379
D
L
Y
P
L
F
A
C
M
L
T
A
R
S
W
Dog
Lupus familis
XP_539216
624
71219
S488
R
L
G
Q
L
W
R
S
H
L
L
S
R
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80V03
582
66636
S444
R
L
G
Q
L
W
G
S
H
L
I
S
R
E
E
Rat
Rattus norvegicus
NP_001129270
582
66734
S444
R
L
G
Q
L
W
G
S
H
L
I
S
R
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507044
482
54419
T370
R
S
S
K
R
V
L
T
A
D
F
C
D
G
C
Chicken
Gallus gallus
Q5ZMT7
519
59182
C376
D
L
Y
P
L
F
A
C
M
L
T
A
R
S
W
Frog
Xenopus laevis
Q6INL7
520
59525
E395
S
V
N
R
G
I
Y
E
N
T
V
S
K
E
E
Zebra Danio
Brachydanio rerio
XP_001341554
579
66788
G444
N
M
W
D
L
G
L
G
N
I
L
T
G
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648446
557
64196
R419
R
N
R
G
G
G
I
R
G
K
L
T
Q
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181542
582
67255
Y460
N
E
L
G
I
E
E
Y
L
L
F
A
M
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
D419
Q
V
I
D
T
S
V
D
H
L
V
I
Q
G
N
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
N435
R
S
I
D
A
A
L
N
Y
D
I
S
T
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
34.4
77
N.A.
80.5
79.3
N.A.
56.2
32.2
32.9
60.5
N.A.
38.9
N.A.
N.A.
41.4
Protein Similarity:
100
99.6
51.7
83.3
N.A.
89
88.1
N.A.
63.7
49.6
51.5
76.5
N.A.
57.2
N.A.
N.A.
60.4
P-Site Identity:
100
100
26.6
93.3
N.A.
93.3
93.3
N.A.
6.6
26.6
20
26.6
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
40
93.3
N.A.
100
100
N.A.
20
40
53.3
53.3
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.7
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
15
0
8
0
0
22
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
8
0
0
8
% C
% Asp:
15
0
0
22
0
0
0
8
0
15
0
0
8
0
8
% D
% Glu:
0
8
0
0
0
8
8
8
0
0
0
0
0
58
50
% E
% Phe:
0
0
0
0
0
15
0
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
36
15
15
15
29
8
8
0
0
0
8
15
0
% G
% His:
0
0
0
0
0
0
0
0
43
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
8
8
8
0
0
8
22
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
0
50
8
0
58
0
22
0
8
65
36
0
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
15
0
0
0
8
8
0
% M
% Asn:
15
8
8
0
0
0
0
8
15
0
0
0
0
0
8
% N
% Pro:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
36
0
0
0
0
0
0
0
0
15
0
0
% Q
% Arg:
58
0
8
8
8
0
8
8
0
0
0
0
50
0
8
% R
% Ser:
8
15
8
0
0
8
0
36
0
0
0
50
0
22
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
8
15
15
8
0
0
% T
% Val:
0
15
0
0
0
8
8
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
8
0
0
36
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
0
15
0
0
0
8
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _