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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D25
All Species:
13.03
Human Site:
S596
Identified Species:
28.67
UniProt:
Q3MII6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MII6
NP_002527.1
688
76357
S596
S
P
K
D
P
G
K
S
L
P
P
V
P
P
M
Chimpanzee
Pan troglodytes
XP_001139235
548
60665
N501
M
R
N
G
L
D
Y
N
E
L
A
M
H
F
D
Rhesus Macaque
Macaca mulatta
XP_001098742
688
76366
S596
S
P
K
D
P
G
K
S
L
P
P
V
P
P
M
Dog
Lupus familis
XP_548985
687
76023
S595
S
P
Q
E
P
G
K
S
L
P
P
P
P
P
L
Cat
Felis silvestris
Mouse
Mus musculus
A1A5B6
742
82556
P650
S
P
R
D
P
G
K
P
V
P
P
P
P
P
M
Rat
Rattus norvegicus
NP_001100425
688
76364
S596
S
P
R
D
P
G
K
S
V
P
P
P
P
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520975
664
74736
G586
P
P
Q
E
F
G
K
G
N
P
F
M
L
F
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121708
863
95814
I723
N
K
P
E
G
G
G
I
K
P
C
S
L
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611029
1098
122546
N1011
P
T
E
F
G
G
G
N
A
F
L
M
F
L
C
Honey Bee
Apis mellifera
XP_395220
875
99616
F622
S
P
D
D
P
T
D
F
F
P
M
T
T
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192002
715
80854
R584
S
P
P
K
S
P
Q
R
P
H
P
M
S
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.1
99.2
94.7
N.A.
87.1
93.5
N.A.
66.7
N.A.
N.A.
56.6
N.A.
27.1
37
N.A.
43.3
Protein Similarity:
100
78.7
99.7
97
N.A.
88.8
95.3
N.A.
75.4
N.A.
N.A.
64.7
N.A.
38.3
50.9
N.A.
59.4
P-Site Identity:
100
0
100
73.3
N.A.
73.3
80
N.A.
26.6
N.A.
N.A.
20
N.A.
6.6
40
N.A.
26.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
93.3
N.A.
53.3
N.A.
N.A.
33.3
N.A.
26.6
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
0
0
10
46
0
10
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
28
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
10
10
10
10
0
10
19
0
% F
% Gly:
0
0
0
10
19
73
19
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
19
10
0
0
55
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
28
10
10
0
19
10
28
% L
% Met:
10
0
0
0
0
0
0
0
0
0
10
37
0
0
46
% M
% Asn:
10
0
10
0
0
0
0
19
10
0
0
0
0
0
0
% N
% Pro:
19
73
19
0
55
10
0
10
10
73
55
28
46
64
10
% P
% Gln:
0
0
19
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
19
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
64
0
0
0
10
0
0
37
0
0
0
10
10
10
0
% S
% Thr:
0
10
0
0
0
10
0
0
0
0
0
10
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
19
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _