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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
14.85
Human Site:
T280
Identified Species:
32.67
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
T280
Y
A
R
E
Q
Q
E
T
N
P
L
F
H
A
F
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
T280
Y
A
R
E
Q
Q
E
T
N
P
L
F
H
A
F
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
T280
Y
A
R
E
Q
Q
E
T
N
P
L
F
H
A
F
Dog
Lupus familis
XP_534913
800
89979
N280
Y
A
R
E
Q
Q
D
N
N
P
L
F
H
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
T280
Y
A
R
E
Q
Q
D
T
N
P
L
F
H
T
F
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
D491
Y
M
R
S
L
L
R
D
N
D
L
F
R
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
E9
L
D
K
M
E
Q
L
E
S
K
L
H
S
Y
S
Chicken
Gallus gallus
XP_423692
451
48811
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
D258
Y
M
R
T
L
L
K
D
N
E
L
F
R
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
T290
H
L
L
Q
G
F
E
T
F
E
Q
T
F
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
E339
Y
V
R
E
K
R
Q
E
N
N
I
L
R
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
100
86.6
N.A.
86.6
40
N.A.
13.3
0
N.A.
33.3
N.A.
N.A.
20
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
46.6
N.A.
33.3
0
N.A.
46.6
N.A.
N.A.
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
0
0
0
0
0
0
0
0
0
64
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
19
19
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
55
10
0
37
19
0
19
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
64
10
0
55
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
10
46
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
10
0
10
0
10
0
0
10
0
0
0
0
0
% K
% Leu:
10
10
10
0
19
19
10
0
0
0
73
10
0
0
0
% L
% Met:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
73
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
10
% P
% Gln:
0
0
0
10
46
55
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
73
0
0
10
10
0
0
0
0
0
28
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
10
0
0
0
10
0
10
% S
% Thr:
0
0
0
10
0
0
0
46
0
0
0
10
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
73
0
0
0
0
0
0
0
0
0
0
0
0
10
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _