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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BSX All Species: 24.55
Human Site: S184 Identified Species: 41.54
UniProt: Q3C1V8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3C1V8 NP_001091639.1 233 25933 S184 K A P D G P E S P E G S P R G
Chimpanzee Pan troglodytes XP_522208 404 43343 S355 K A P E G P E S P E G S P R G
Rhesus Macaque Macaca mulatta XP_001107998 232 25875 S184 K A P D G P E S P E G S P R G
Dog Lupus familis XP_546472 232 25894 S184 K A P D G P E S P E G S P R G
Cat Felis silvestris
Mouse Mus musculus Q810B3 232 25844 S184 K A A D G P E S P E G S P R A
Rat Rattus norvegicus O88181 384 41445 S317 S P Y F Y H P S L L G S M D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513130 410 44056 S363 K A P D G S E S S E R S P R G
Chicken Gallus gallus Q6RFL5 233 26434 Q186 I H E E N R E Q S S P E P E L
Frog Xenopus laevis Q8JJ64 306 34004 V257 A A Q R I V R V P I L Y H E N
Zebra Danio Brachydanio rerio Q6R3Q6 227 26450 R179 K T P N D V D R S L E N T S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q04787 429 45696 S348 E P V D F S R S E P G K Q P G
Honey Bee Apis mellifera XP_001120703 282 30987 S182 G S N G N Q N S N Q Q C T G Q
Nematode Worm Caenorhab. elegans Q22909 237 26113 A169 S E P G N L S A V Q N L I R S
Sea Urchin Strong. purpuratus XP_798061 334 36314 K260 T K P K G R P K K S D I T G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.4 98.7 96.5 N.A. 95.7 25.7 N.A. 28.7 78.1 27.7 66 N.A. 31 36.1 27.8 28.1
Protein Similarity: 100 57.6 98.7 97.8 N.A. 96.1 34.6 N.A. 37.3 83.6 37.9 77.6 N.A. 37.7 43.2 43.4 41.9
P-Site Identity: 100 93.3 100 100 N.A. 86.6 20 N.A. 80 13.3 13.3 13.3 N.A. 26.6 6.6 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 20 N.A. 80 20 13.3 33.3 N.A. 33.3 20 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 50 8 0 0 0 0 8 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 43 8 0 8 0 0 0 8 0 0 8 0 % D
% Glu: 8 8 8 15 0 0 50 0 8 43 8 8 0 15 15 % E
% Phe: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 15 50 0 0 0 0 0 50 0 0 15 43 % G
% His: 0 8 0 0 0 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 8 0 0 0 0 8 0 8 8 0 0 % I
% Lys: 50 8 0 8 0 0 0 8 8 0 0 8 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 0 8 15 8 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 8 8 22 0 8 0 8 0 8 8 0 0 8 % N
% Pro: 0 15 58 0 0 36 15 0 43 8 8 0 50 8 0 % P
% Gln: 0 0 8 0 0 8 0 8 0 15 8 0 8 0 8 % Q
% Arg: 0 0 0 8 0 15 15 8 0 0 8 0 0 50 0 % R
% Ser: 15 8 0 0 0 15 8 65 22 15 0 50 0 8 15 % S
% Thr: 8 8 0 0 0 0 0 0 0 0 0 0 22 0 0 % T
% Val: 0 0 8 0 0 15 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _