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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM161A
All Species:
25.45
Human Site:
S258
Identified Species:
56
UniProt:
Q3B820
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3B820
NP_115556.2
660
76752
S258
K
K
E
E
S
M
K
S
K
S
D
I
E
M
V
Chimpanzee
Pan troglodytes
XP_515502
810
93692
S352
K
K
E
E
S
M
K
S
K
S
D
I
E
M
V
Rhesus Macaque
Macaca mulatta
XP_001114142
716
83631
S258
K
K
E
E
S
M
K
S
K
S
D
I
E
M
V
Dog
Lupus familis
XP_538506
813
93838
S378
K
K
E
E
N
M
K
S
K
S
D
I
E
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZV6
448
52011
Q103
F
S
V
E
D
Y
I
Q
Y
D
S
D
S
R
T
Rat
Rattus norvegicus
Q6AY14
422
48850
S78
P
G
E
I
G
T
R
S
Y
A
K
E
L
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512552
616
72359
K239
R
A
N
T
L
L
R
K
Q
E
E
E
A
E
A
Chicken
Gallus gallus
XP_001232414
818
93165
S298
R
K
E
Q
K
V
K
S
K
S
Q
I
E
M
E
Frog
Xenopus laevis
Q66KE9
647
75309
S245
K
R
E
M
N
I
K
S
K
S
E
I
E
L
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625188
369
43344
M25
I
S
N
S
T
E
D
M
D
I
F
L
E
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797361
773
89468
T341
S
S
E
E
R
K
K
T
R
A
S
M
E
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.3
87.4
57.6
N.A.
39
31.8
N.A.
46
37.5
41.8
N.A.
N.A.
N.A.
21.2
N.A.
24
Protein Similarity:
100
80.6
88.1
67
N.A.
51
44.7
N.A.
61.9
53.6
61.2
N.A.
N.A.
N.A.
35.7
N.A.
45.2
P-Site Identity:
100
100
100
93.3
N.A.
6.6
13.3
N.A.
0
60
53.3
N.A.
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
6.6
33.3
N.A.
33.3
80
86.6
N.A.
N.A.
N.A.
26.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
19
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
10
10
37
10
0
0
0
% D
% Glu:
0
0
73
55
0
10
0
0
0
10
19
19
73
10
28
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
10
10
0
0
10
0
55
0
10
0
% I
% Lys:
46
46
0
0
10
10
64
10
55
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
10
10
0
0
0
0
0
10
10
19
10
% L
% Met:
0
0
0
10
0
37
0
10
0
0
0
10
0
46
0
% M
% Asn:
0
0
19
0
19
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
10
0
10
0
0
0
0
% Q
% Arg:
19
10
0
0
10
0
19
0
10
0
0
0
0
10
0
% R
% Ser:
10
28
0
10
28
0
0
64
0
55
19
0
10
0
0
% S
% Thr:
0
0
0
10
10
10
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _