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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFX4
All Species:
20.91
Human Site:
Y86
Identified Species:
51.11
UniProt:
Q33E94
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q33E94
NP_002911.2
735
83395
Y86
R
S
A
L
Y
M
H
Y
L
D
F
C
E
K
N
Chimpanzee
Pan troglodytes
XP_001161826
725
82224
E81
M
H
Y
L
D
F
C
E
K
N
D
T
Q
P
V
Rhesus Macaque
Macaca mulatta
XP_001100097
728
82503
E81
M
H
Y
L
D
F
C
E
K
N
D
T
Q
P
V
Dog
Lupus familis
XP_851020
725
82154
E81
M
H
Y
L
D
F
C
E
K
N
D
T
Q
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNK1
735
83353
Y86
R
S
A
L
Y
M
H
Y
L
D
F
C
E
K
N
Rat
Rattus norvegicus
XP_576205
646
73446
G26
M
E
T
S
C
P
L
G
R
D
L
T
E
W
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508397
939
105225
Y289
R
S
A
L
Y
M
H
Y
L
D
F
C
E
K
N
Chicken
Gallus gallus
XP_416306
784
88581
Y135
R
S
A
L
Y
M
H
Y
L
D
F
C
E
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGA0
735
82801
Y86
R
S
A
L
Y
M
H
Y
L
D
F
C
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790469
942
105870
Y125
R
C
I
L
Y
S
H
Y
L
D
F
C
R
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.8
97.1
N.A.
97
80.5
N.A.
75.2
88.6
N.A.
84.4
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
98.6
97.9
97.8
N.A.
98.7
82.9
N.A.
77
91.1
N.A.
91.4
N.A.
N.A.
N.A.
N.A.
46.7
P-Site Identity:
100
6.6
6.6
6.6
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
20
20
20
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
10
0
30
0
0
0
0
60
0
0
0
% C
% Asp:
0
0
0
0
30
0
0
0
0
70
30
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
30
0
0
0
0
60
0
10
% E
% Phe:
0
0
0
0
0
30
0
0
0
0
60
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
30
0
0
0
0
60
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
30
0
0
0
0
60
0
% K
% Leu:
0
0
0
90
0
0
10
0
60
0
10
0
0
0
10
% L
% Met:
40
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
40
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
30
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% Q
% Arg:
60
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
0
50
0
10
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
40
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
30
0
60
0
0
60
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _