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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGS1
All Species:
13.64
Human Site:
S441
Identified Species:
27.27
UniProt:
Q32NB8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q32NB8
NP_077733.3
556
62730
S441
H
I
E
R
Q
F
F
S
E
V
C
S
L
G
Q
Chimpanzee
Pan troglodytes
XP_001157355
556
62742
S441
H
I
E
R
Q
F
Y
S
E
V
C
S
L
G
Q
Rhesus Macaque
Macaca mulatta
XP_001108217
556
62744
S441
H
I
E
R
Q
F
Y
S
E
V
C
S
L
G
Q
Dog
Lupus familis
XP_533128
623
69964
R508
H
I
E
R
Q
F
Y
R
E
V
C
S
L
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHF7
553
62471
S438
H
I
E
R
Q
F
Y
S
E
V
C
S
L
G
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520615
590
65217
G431
R
F
P
S
R
E
A
G
V
D
P
A
Y
G
R
Chicken
Gallus gallus
Q5ZHN9
557
63048
N442
Y
I
E
H
Q
F
Y
N
E
V
C
C
L
H
Q
Frog
Xenopus laevis
NP_001086803
413
47224
K300
V
N
G
F
F
G
A
K
G
I
A
G
A
I
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650751
494
56409
E382
L
I
A
K
S
F
Y
E
S
L
V
R
R
K
Q
Honey Bee
Apis mellifera
XP_397318
473
54471
N361
L
E
E
S
F
V
K
N
C
N
K
L
G
Q
Q
Nematode Worm
Caenorhab. elegans
NP_490666
446
51683
L334
S
N
I
S
D
Q
F
L
R
K
R
E
I
N
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25578
521
59352
I405
R
Y
R
Q
D
H
A
I
T
L
R
E
W
Q
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.3
85.3
N.A.
94.2
N.A.
N.A.
60
81.5
54.1
N.A.
N.A.
40.8
38.3
32.5
N.A.
Protein Similarity:
100
100
99.4
88.2
N.A.
98.5
N.A.
N.A.
72.8
90.3
64.5
N.A.
N.A.
58.2
54.3
50.5
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
93.3
N.A.
N.A.
6.6
60
0
N.A.
N.A.
20
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
26.6
80
6.6
N.A.
N.A.
40
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
25
0
0
0
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
50
9
0
0
0
% C
% Asp:
0
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
9
59
0
0
9
0
9
50
0
0
17
0
0
0
% E
% Phe:
0
9
0
9
17
59
17
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
9
9
0
0
9
9
50
9
% G
% His:
42
0
0
9
0
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
59
9
0
0
0
0
9
0
9
0
0
9
9
0
% I
% Lys:
0
0
0
9
0
0
9
9
0
9
9
0
0
9
0
% K
% Leu:
17
0
0
0
0
0
0
9
0
17
0
9
50
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
17
0
9
0
0
0
9
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
9
% P
% Gln:
0
0
0
9
50
9
0
0
0
0
0
0
0
17
67
% Q
% Arg:
17
0
9
42
9
0
0
9
9
0
17
9
9
0
17
% R
% Ser:
9
0
0
25
9
0
0
34
9
0
0
42
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
9
0
0
9
50
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
9
9
0
0
0
0
50
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _