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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO4
All Species:
22.73
Human Site:
Y125
Identified Species:
50
UniProt:
Q32M45
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q32M45
NP_849148.2
955
111462
Y125
R
I
D
Y
I
L
V
Y
R
K
S
N
P
Q
T
Chimpanzee
Pan troglodytes
XP_509302
955
111457
Y125
R
I
D
Y
I
L
V
Y
R
K
S
N
P
Q
T
Rhesus Macaque
Macaca mulatta
XP_001090523
955
111458
Y125
R
I
D
Y
I
L
V
Y
R
K
S
N
P
Q
T
Dog
Lupus familis
XP_854987
931
108790
R116
E
K
R
E
V
F
E
R
N
I
R
A
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5H1
955
111525
Y125
R
I
D
Y
I
L
V
Y
R
K
S
N
P
Q
T
Rat
Rattus norvegicus
Q6IFT6
860
97152
E105
D
Q
R
D
V
Q
D
E
A
A
A
V
H
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506513
1182
136128
Y352
R
I
D
Y
I
L
V
Y
R
K
S
S
P
Q
T
Chicken
Gallus gallus
XP_425452
976
114472
Y146
R
I
D
Y
I
L
V
Y
R
K
S
N
P
Q
T
Frog
Xenopus laevis
NP_001086810
896
105149
L123
I
H
A
P
W
E
V
L
T
T
Y
A
E
V
L
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
Q116
N
L
I
D
E
G
L
Q
L
E
Y
E
N
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.7
94.6
N.A.
98.3
35.7
N.A.
77.5
88.7
43.9
24.5
N.A.
N.A.
N.A.
N.A.
42.9
Protein Similarity:
100
100
99.9
95.8
N.A.
99
53.6
N.A.
79.2
92.6
62.6
39.6
N.A.
N.A.
N.A.
N.A.
61.2
P-Site Identity:
100
100
100
0
N.A.
100
0
N.A.
93.3
100
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
100
13.3
N.A.
100
100
6.6
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
10
10
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
55
19
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
10
10
10
10
0
10
0
10
19
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
55
10
0
55
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
0
10
0
0
0
0
0
0
0
55
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
55
10
10
10
0
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
10
0
0
46
10
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
55
0
0
% P
% Gln:
0
10
0
0
0
10
0
10
0
0
0
0
0
55
0
% Q
% Arg:
55
0
19
0
0
0
0
10
55
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
55
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
55
% T
% Val:
0
0
0
0
19
0
64
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
55
0
0
0
55
0
0
19
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _