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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO4
All Species:
18.18
Human Site:
T496
Identified Species:
40
UniProt:
Q32M45
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q32M45
NP_849148.2
955
111462
T496
P
E
P
Y
Q
A
F
T
D
K
C
S
R
L
I
Chimpanzee
Pan troglodytes
XP_509302
955
111457
T496
P
E
P
Y
Q
A
F
T
D
K
C
S
R
L
I
Rhesus Macaque
Macaca mulatta
XP_001090523
955
111458
T496
P
E
P
Y
Q
A
F
T
D
K
C
S
R
L
I
Dog
Lupus familis
XP_854987
931
108790
A472
P
E
P
Y
Q
A
F
A
D
K
C
S
R
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5H1
955
111525
T496
P
E
P
Y
Q
A
F
T
D
K
C
S
R
L
I
Rat
Rattus norvegicus
Q6IFT6
860
97152
V458
A
V
V
I
M
C
L
V
S
I
I
L
Y
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506513
1182
136128
T723
P
E
P
Y
Q
A
F
T
D
K
C
S
R
L
V
Chicken
Gallus gallus
XP_425452
976
114472
A517
P
E
P
Y
Q
A
F
A
D
K
C
S
R
L
I
Frog
Xenopus laevis
NP_001086810
896
105149
R486
N
L
T
L
E
P
V
R
N
L
L
T
P
Q
L
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
L245
E
D
Y
D
K
Y
V
L
F
A
V
F
N
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
A470
R
K
F
P
R
F
S
A
S
I
A
S
I
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.7
94.6
N.A.
98.3
35.7
N.A.
77.5
88.7
43.9
24.5
N.A.
N.A.
N.A.
N.A.
42.9
Protein Similarity:
100
100
99.9
95.8
N.A.
99
53.6
N.A.
79.2
92.6
62.6
39.6
N.A.
N.A.
N.A.
N.A.
61.2
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
93.3
93.3
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
0
N.A.
100
93.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
64
0
28
0
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
64
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
64
0
0
0
0
0
0
% D
% Glu:
10
64
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
10
64
0
10
0
0
10
0
10
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
19
10
0
10
0
55
% I
% Lys:
0
10
0
0
10
0
0
0
0
64
0
0
0
0
0
% K
% Leu:
0
10
0
10
0
0
10
10
0
10
10
10
0
73
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% N
% Pro:
64
0
64
10
0
10
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
64
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
0
0
10
0
0
10
0
0
0
0
64
10
0
% R
% Ser:
0
0
0
0
0
0
10
0
19
0
0
73
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
46
0
0
0
10
0
0
0
% T
% Val:
0
10
10
0
0
0
19
10
0
0
10
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
64
0
10
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _