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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM2
All Species:
5.45
Human Site:
S277
Identified Species:
13.33
UniProt:
Q2VYF4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VYF4
NP_653253.1
491
55921
S277
T
K
E
I
V
R
F
S
K
L
F
E
D
Q
L
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
H241
E
D
Q
L
A
L
E
H
L
D
R
P
Q
L
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532802
593
66182
H371
E
D
Q
L
T
L
E
H
L
D
R
P
Q
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNU7
480
54440
S275
T
K
E
I
V
R
F
S
K
L
F
K
D
Q
L
Rat
Rattus norvegicus
Q5PQQ5
459
52505
S251
R
A
K
L
D
D
D
S
S
D
S
S
Q
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK33
752
85831
F305
S
N
E
E
I
L
R
F
S
K
L
F
E
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
F315
S
N
E
Q
I
I
R
F
S
K
L
F
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
F336
S
N
D
E
I
I
K
F
A
K
R
F
D
D
E
Honey Bee
Apis mellifera
XP_624231
764
87758
F272
T
N
E
E
I
M
Q
F
S
K
L
F
E
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
E338
D
K
I
L
E
T
G
E
Q
A
S
N
E
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
N.A.
46.7
N.A.
77.5
73.1
N.A.
N.A.
33.6
N.A.
31.9
N.A.
23.3
28.1
N.A.
37.5
Protein Similarity:
100
89.6
N.A.
56.6
N.A.
83.3
79.4
N.A.
N.A.
46.5
N.A.
47.1
N.A.
33.1
41.3
N.A.
55.1
P-Site Identity:
100
0
N.A.
0
N.A.
93.3
6.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
20
N.A.
20
N.A.
100
20
N.A.
N.A.
26.6
N.A.
26.6
N.A.
26.6
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
20
10
0
10
10
10
0
0
30
0
0
30
40
0
% D
% Glu:
20
0
50
30
10
0
20
10
0
0
0
10
40
10
40
% E
% Phe:
0
0
0
0
0
0
20
40
0
0
20
40
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
20
40
20
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
30
10
0
0
0
10
0
20
40
0
10
0
0
0
% K
% Leu:
0
0
0
40
0
30
0
0
20
20
30
0
0
30
20
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% P
% Gln:
0
0
20
10
0
0
10
0
10
0
0
0
30
20
0
% Q
% Arg:
10
0
0
0
0
20
20
0
0
0
30
0
0
0
0
% R
% Ser:
30
0
0
0
0
0
0
30
40
0
20
10
0
0
10
% S
% Thr:
30
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _