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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
36.97
Human Site:
Y43
Identified Species:
73.94
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
Y43
P
Q
D
I
D
E
R
Y
C
L
A
L
G
E
E
Chimpanzee
Pan troglodytes
XP_518466
564
60722
Y262
P
Q
D
I
D
E
R
Y
C
L
A
L
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
Y83
P
Q
D
I
D
E
H
Y
C
L
A
L
G
E
E
Dog
Lupus familis
XP_538916
439
47231
Y143
P
Q
D
S
D
E
R
Y
C
L
A
F
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
Y89
P
H
D
N
E
V
R
Y
C
N
S
L
D
E
E
Rat
Rattus norvegicus
Q71QF9
831
94152
Y85
P
H
D
N
E
V
R
Y
C
Q
S
L
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
Y129
P
H
D
N
E
V
R
Y
C
N
S
L
D
E
E
Chicken
Gallus gallus
XP_001234704
864
97886
Y117
P
H
D
N
E
V
R
Y
C
N
S
L
D
E
E
Frog
Xenopus laevis
Q90Z06
835
94992
Y85
P
H
D
N
E
V
R
Y
C
Q
S
L
S
E
E
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
Y106
P
H
D
N
E
I
R
Y
C
Q
S
L
S
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
Y206
P
Q
D
N
E
V
R
Y
C
H
S
L
S
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
Y211
P
H
D
N
E
V
R
Y
C
N
G
L
G
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
100
93.3
73.3
N.A.
53.3
53.3
N.A.
53.3
53.3
53.3
46.6
N.A.
53.3
N.A.
N.A.
53.3
P-Site Similarity:
100
100
93.3
80
N.A.
66.6
66.6
N.A.
66.6
66.6
66.6
66.6
N.A.
73.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% C
% Asp:
0
0
100
0
34
0
0
0
0
0
0
0
25
17
17
% D
% Glu:
0
0
0
0
67
34
0
0
0
0
0
0
9
84
84
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
34
0
0
% G
% His:
0
59
0
0
0
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
25
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
34
0
92
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
67
0
0
0
0
0
34
0
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
42
0
0
0
0
0
0
0
25
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
0
0
0
0
59
0
34
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _