KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
10.61
Human Site:
T297
Identified Species:
21.21
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
T297
T
I
R
D
P
K
D
T
P
F
S
T
C
S
S
Chimpanzee
Pan troglodytes
XP_518466
564
60722
T517
T
I
R
D
P
K
D
T
P
F
S
T
C
S
S
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
T338
T
L
C
D
S
K
D
T
P
F
S
T
C
S
S
Dog
Lupus familis
XP_538916
439
47231
A392
P
L
D
A
R
E
D
A
P
C
P
T
C
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
D774
G
P
Y
F
T
E
Y
D
W
C
S
T
C
S
S
Rat
Rattus norvegicus
Q71QF9
831
94152
S761
L
Y
G
D
D
D
D
S
W
C
S
S
S
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
D811
R
P
Y
F
A
E
Y
D
W
C
S
T
C
S
S
Chicken
Gallus gallus
XP_001234704
864
97886
D793
G
P
Y
F
A
E
Y
D
W
C
S
T
C
S
S
Frog
Xenopus laevis
Q90Z06
835
94992
W765
Y
G
E
D
E
D
S
W
C
S
T
C
S
S
S
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
W805
D
D
D
E
E
D
D
W
C
S
T
C
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
N676
S
S
S
E
M
Q
I
N
Q
T
N
L
R
L
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
F727
M
S
R
S
A
S
H
F
D
R
R
A
D
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
100
80
40
N.A.
33.3
26.6
N.A.
33.3
33.3
20
20
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
53.3
N.A.
40
46.6
N.A.
40
40
26.6
33.3
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
25
0
0
9
0
0
0
9
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
17
42
0
17
59
0
0
% C
% Asp:
9
9
17
42
9
25
50
25
9
0
0
0
9
0
0
% D
% Glu:
0
0
9
17
17
34
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
25
0
0
0
9
0
25
0
0
0
0
0
% F
% Gly:
17
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
0
17
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
17
0
0
0
0
0
0
0
0
0
9
0
9
0
% L
% Met:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
9
25
0
0
17
0
0
0
34
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
25
0
9
0
0
0
0
9
9
0
9
0
0
% R
% Ser:
9
17
9
9
9
9
9
9
0
17
59
9
25
75
84
% S
% Thr:
25
0
0
0
9
0
0
25
0
9
17
59
0
17
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
17
34
0
0
0
0
0
0
% W
% Tyr:
9
9
25
0
0
0
25
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _