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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
15.76
Human Site:
S334
Identified Species:
31.52
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
S334
G
S
L
Q
A
E
D
S
N
A
S
K
T
H
C
Chimpanzee
Pan troglodytes
XP_518466
564
60722
S554
G
S
L
Q
A
E
D
S
N
A
S
K
T
H
C
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
S375
G
S
L
Q
A
E
D
S
N
A
S
K
K
H
C
Dog
Lupus familis
XP_538916
439
47231
S429
G
S
L
Q
A
G
D
S
D
T
S
R
R
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
L811
Y
V
T
S
D
E
L
L
H
K
Y
S
S
Y
G
Rat
Rattus norvegicus
Q71QF9
831
94152
L798
F
T
Y
Y
T
D
D
L
S
S
P
A
S
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
L848
Y
V
T
S
E
E
L
L
H
K
Y
G
S
Y
G
Chicken
Gallus gallus
XP_001234704
864
97886
L830
Y
V
T
S
E
E
L
L
H
K
Y
G
S
Y
S
Frog
Xenopus laevis
Q90Z06
835
94992
L802
Y
Q
Y
F
S
D
D
L
C
S
P
T
N
A
L
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
Y842
F
H
Y
Y
T
E
D
Y
P
T
R
V
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
S713
A
S
I
C
S
T
C
S
S
S
S
S
S
D
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
R764
M
K
Y
D
K
Y
N
R
Y
E
D
D
D
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
100
93.3
66.6
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
20
N.A.
20
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
80
N.A.
26.6
40
N.A.
26.6
26.6
26.6
20
N.A.
53.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
34
0
0
0
0
25
0
9
0
25
0
% A
% Cys:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
34
% C
% Asp:
0
0
0
9
9
17
59
0
9
0
9
9
9
9
0
% D
% Glu:
0
0
0
0
17
59
0
0
0
9
0
0
0
0
0
% E
% Phe:
17
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
0
0
0
9
0
0
0
0
0
17
0
0
17
% G
% His:
0
9
0
0
0
0
0
0
25
0
0
0
0
34
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
0
0
0
0
25
0
25
9
0
0
% K
% Leu:
0
0
34
0
0
0
25
42
0
0
0
0
0
0
25
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
9
0
25
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
17
0
0
0
0
% P
% Gln:
0
9
0
34
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
9
9
9
0
0
% R
% Ser:
0
42
0
25
17
0
0
42
17
25
42
17
42
0
17
% S
% Thr:
0
9
25
0
17
9
0
0
0
17
0
9
25
0
0
% T
% Val:
0
25
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
34
17
0
9
0
9
9
0
25
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _