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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
31.21
Human Site:
S303
Identified Species:
62.42
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
S303
D
T
P
F
S
T
C
S
S
S
S
D
S
E
P
Chimpanzee
Pan troglodytes
XP_518466
564
60722
S523
D
T
P
F
S
T
C
S
S
S
S
D
S
E
P
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
S344
D
T
P
F
S
T
C
S
S
S
S
D
S
E
P
Dog
Lupus familis
XP_538916
439
47231
S398
D
A
P
C
P
T
C
S
S
S
S
D
S
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
S780
Y
D
W
C
S
T
C
S
S
S
S
E
S
D
N
Rat
Rattus norvegicus
Q71QF9
831
94152
T767
D
S
W
C
S
S
S
T
S
S
S
D
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
S817
Y
D
W
C
S
T
C
S
S
S
S
E
S
D
N
Chicken
Gallus gallus
XP_001234704
864
97886
S799
Y
D
W
C
S
T
C
S
S
S
S
E
S
D
N
Frog
Xenopus laevis
Q90Z06
835
94992
S771
S
W
C
S
T
C
S
S
S
S
S
D
S
E
E
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
S811
D
W
C
S
T
C
S
S
S
S
S
E
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
L682
I
N
Q
T
N
L
R
L
H
N
A
Q
T
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
T733
H
F
D
R
R
A
D
T
Y
H
S
E
R
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
100
100
80
N.A.
53.3
53.3
N.A.
53.3
53.3
46.6
46.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
66.6
73.3
N.A.
66.6
66.6
53.3
60
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
17
42
0
17
59
0
0
0
0
0
0
0
0
% C
% Asp:
50
25
9
0
0
0
9
0
0
0
0
50
0
25
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
42
0
59
25
% E
% Phe:
0
9
0
25
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
9
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
9
0
0
0
0
25
% N
% Pro:
0
0
34
0
9
0
0
0
0
0
0
0
0
0
34
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
0
9
9
0
9
0
0
0
0
0
9
0
9
% R
% Ser:
9
9
0
17
59
9
25
75
84
84
92
0
84
0
0
% S
% Thr:
0
25
0
9
17
59
0
17
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
17
34
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _