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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
1.21
Human Site:
S265
Identified Species:
2.42
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
S265
T
Q
R
G
L
P
G
S
S
P
Q
Q
E
N
R
Chimpanzee
Pan troglodytes
XP_518466
564
60722
G484
Q
T
Q
R
G
L
P
G
S
S
P
Q
Q
E
N
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
G305
Q
T
Q
T
G
L
P
G
S
S
P
Q
Q
E
N
Dog
Lupus familis
XP_538916
439
47231
D365
P
S
S
P
E
Q
E
D
R
A
G
D
R
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
G513
E
E
E
E
E
E
G
G
I
S
T
Q
Q
C
R
Rat
Rattus norvegicus
Q71QF9
831
94152
M437
Q
P
P
S
E
V
D
M
R
A
S
E
H
W
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
S351
I
F
C
S
R
A
C
S
A
G
E
D
P
N
G
Chicken
Gallus gallus
XP_001234704
864
97886
L406
L
Q
M
D
L
L
S
L
A
S
Q
T
P
S
L
Frog
Xenopus laevis
Q90Z06
835
94992
E601
S
L
K
S
L
N
S
E
I
C
Q
E
K
P
P
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
E617
S
L
R
S
L
N
S
E
L
G
H
E
E
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
G460
I
A
K
S
P
R
R
G
G
E
R
E
R
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
G504
S
L
P
D
L
R
N
G
S
S
T
D
Y
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
13.3
13.3
0
N.A.
20
0
N.A.
13.3
20
13.3
20
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
26.6
26.6
0
N.A.
33.3
6.6
N.A.
26.6
33.3
40
33.3
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
0
17
17
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
9
0
0
9
0
0
0
9
0
% C
% Asp:
0
0
0
17
0
0
9
9
0
0
0
25
0
9
0
% D
% Glu:
9
9
9
9
25
9
9
17
0
9
9
34
17
17
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
17
0
17
42
9
17
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
17
0
0
0
0
0
9
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
25
0
0
42
25
0
9
9
0
0
0
0
0
17
% L
% Met:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
9
0
0
0
0
0
0
17
17
% N
% Pro:
9
9
17
9
9
9
17
0
0
9
17
0
17
9
17
% P
% Gln:
25
17
17
0
0
9
0
0
0
0
25
34
25
0
0
% Q
% Arg:
0
0
17
9
9
17
9
0
17
0
9
0
17
0
25
% R
% Ser:
25
9
9
42
0
0
25
17
34
42
9
0
0
17
0
% S
% Thr:
9
17
0
9
0
0
0
0
0
0
17
9
0
17
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _