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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG2A All Species: 19.7
Human Site: S254 Identified Species: 39.39
UniProt: Q2TAZ0 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAZ0 NP_055919 1938 212919 S254 E P P L Q I G S C S G Y M E L
Chimpanzee Pan troglodytes XP_508535 1868 205411 N238 E G L A D K L N K S R P L G A
Rhesus Macaque Macaca mulatta XP_001114733 1938 213060 S254 E P P L Q I G S C S G Y M E L
Dog Lupus familis XP_540877 1960 215268 S286 K P P L Q I G S C S G Y M E L
Cat Felis silvestris
Mouse Mus musculus Q6P4T0 1914 210921 S254 Q P P L Q I G S C T G Y V E L
Rat Rattus norvegicus NP_001103015 1916 211346 S254 K P P L Q I G S C T G Y M E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512043 2088 234252 R298 S D P V Q I G R L I G R M E L
Chicken Gallus gallus XP_421350 2043 229447 K287 S D P V Q I S K L I G R M D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664934 1738 194462 S187 S K G R C D E S R P E L V L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647748 1906 214898 G241 K H N L V I E G L S L H T S E
Honey Bee Apis mellifera XP_001122229 1976 220972 T257 T F S R S I I T S S R G S T P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792926 2119 235171 E293 L G S C L V G E C A G K Q E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 97.6 89.5 N.A. 84.7 85.1 N.A. 41.3 42 N.A. 36.5 N.A. 28.5 31.1 N.A. 30.9
Protein Similarity: 100 91.4 98.2 92.5 N.A. 90.4 90.4 N.A. 57.3 59.3 N.A. 51.9 N.A. 47 48.7 N.A. 48.8
P-Site Identity: 100 13.3 100 93.3 N.A. 80 86.6 N.A. 53.3 40 N.A. 6.6 N.A. 20 13.3 N.A. 33.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 60 53.3 N.A. 13.3 N.A. 33.3 20 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 9 9 0 0 0 50 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 9 9 0 0 0 0 0 0 0 9 0 % D
% Glu: 25 0 0 0 0 0 17 9 0 0 9 0 0 59 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 9 0 0 0 59 9 0 0 67 9 0 9 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 75 9 0 0 17 0 0 0 0 0 % I
% Lys: 25 9 0 0 0 9 0 9 9 0 0 9 0 0 0 % K
% Leu: 9 0 9 50 9 0 9 0 25 0 9 9 9 9 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % M
% Asn: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 42 59 0 0 0 0 0 0 9 0 9 0 0 9 % P
% Gln: 9 0 0 0 59 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 17 0 0 0 9 9 0 17 17 0 0 9 % R
% Ser: 25 0 17 0 9 0 9 50 9 50 0 0 9 9 0 % S
% Thr: 9 0 0 0 0 0 0 9 0 17 0 0 9 9 0 % T
% Val: 0 0 0 17 9 9 0 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _