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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMU1 All Species: 40
Human Site: S349 Identified Species: 58.67
UniProt: Q2TAY7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAY7 NP_060695.2 513 57544 S349 L K E F R G H S S F V N E A T
Chimpanzee Pan troglodytes XP_001158775 515 57712 S349 L K E F R G H S S F V N E A T
Rhesus Macaque Macaca mulatta XP_001101208 457 51372 E303 G Q C L R R F E R A H S K G V
Dog Lupus familis XP_531971 513 57539 S349 L K E F R G H S S F V N E A T
Cat Felis silvestris
Mouse Mus musculus Q9D7H2 328 36014 N174 P I S A V N F N C N G S L I V
Rat Rattus norvegicus Q99M63 513 57532 S349 L K E F R G H S S F V N E A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515411 513 57497 S349 L K E F R G H S S F V N E A T
Chicken Gallus gallus Q5ZME8 513 57479 S349 L K E F R G H S S F V N E A T
Frog Xenopus laevis Q6NRT3 513 57604 S349 L K E F R G H S S F V N E A T
Zebra Danio Brachydanio rerio Q7ZVA0 513 57512 S349 L K E F R G H S S F V N E A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 N207 P V S A V H F N R D G S L I V
Honey Bee Apis mellifera XP_393446 510 57135 A349 L K E F R G H A S F V N E V V
Nematode Worm Caenorhab. elegans Q93847 395 43110 N241 P V S S V C F N R D G A Y L A
Sea Urchin Strong. purpuratus XP_780200 513 57047 T349 L K E F R G H T S F V N E A V
Poplar Tree Populus trichocarpa XP_002317691 512 57720 A348 L K E F R G H A S Y V N D A I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177513 511 57705 T347 L K E F R G H T S Y V N H A I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 88.8 99.8 N.A. 22.4 99.6 N.A. 99.6 99.6 98.8 95.5 N.A. 23.2 84.5 24.7 83.8
Protein Similarity: 100 99.6 89 100 N.A. 38.7 99.6 N.A. 100 100 98.8 98.2 N.A. 40.3 92.1 42.2 92.4
P-Site Identity: 100 100 6.6 100 N.A. 0 100 N.A. 100 100 100 100 N.A. 0 80 0 86.6
P-Site Similarity: 100 100 26.6 100 N.A. 13.3 100 N.A. 100 100 100 100 N.A. 13.3 86.6 6.6 93.3
Percent
Protein Identity: 66.2 N.A. N.A. 64.7 N.A. N.A.
Protein Similarity: 82.2 N.A. N.A. 81 N.A. N.A.
P-Site Identity: 73.3 N.A. N.A. 73.3 N.A. N.A.
P-Site Similarity: 93.3 N.A. N.A. 86.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 0 0 13 0 7 0 7 0 69 7 % A
% Cys: 0 0 7 0 0 7 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 13 0 0 7 0 0 % D
% Glu: 0 0 75 0 0 0 0 7 0 0 0 0 63 0 0 % E
% Phe: 0 0 0 75 0 0 25 0 0 63 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 75 0 0 0 0 19 0 0 7 0 % G
% His: 0 0 0 0 0 7 75 0 0 0 7 0 7 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 13 13 % I
% Lys: 0 75 0 0 0 0 0 0 0 0 0 0 7 0 0 % K
% Leu: 75 0 0 7 0 0 0 0 0 0 0 0 13 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 19 0 7 0 75 0 0 0 % N
% Pro: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 82 7 0 0 19 0 0 0 0 0 0 % R
% Ser: 0 0 19 7 0 0 0 50 75 0 0 19 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 50 % T
% Val: 0 13 0 0 19 0 0 0 0 0 75 0 0 7 32 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 13 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _