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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS4L2 All Species: 17.88
Human Site: S56 Identified Species: 49.17
UniProt: Q2T9F4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2T9F4 NP_291025 439 48884 S56 S R R Y G P W S I V P I P S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092200 963 108141 S266 V S Q L Y P E S I V P I P S S
Dog Lupus familis XP_534000 964 108247 S267 V S Q L Y P E S I V P I P S S
Cat Felis silvestris
Mouse Mus musculus Q8CIM8 964 108174 S267 V S Q L Y P E S I V P I P S S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417220 941 105375 S280 L S Q L Y P E S I V P I P S S
Frog Xenopus laevis Q68F70 969 109237 S268 L S Q L Y S E S I V P I P S S
Zebra Danio Brachydanio rerio XP_001923719 978 109163 S275 L S Q L Y P E S I V P I P S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623793 916 101959 D72 Q L L V R I S D T I A Y I S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198975 847 94130 P152 G Q V H P D E P V S A P G T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 42.2 41.7 N.A. 41.7 N.A. N.A. N.A. 42.1 37.6 37.2 N.A. N.A. 24.3 N.A. 32.4
Protein Similarity: 100 N.A. 43.4 42.9 N.A. 42.9 N.A. N.A. N.A. 43.8 41.1 41.3 N.A. N.A. 34.8 N.A. 39.9
P-Site Identity: 100 N.A. 60 60 N.A. 60 N.A. N.A. N.A. 60 53.3 60 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 66.6 66.6 N.A. 66.6 N.A. N.A. N.A. 66.6 60 66.6 N.A. N.A. 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 12 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 78 12 0 78 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 34 12 12 67 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 67 0 12 0 0 78 12 78 0 0 % P
% Gln: 12 12 67 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 12 12 0 12 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 67 0 0 0 12 12 78 0 12 0 0 0 89 100 % S
% Thr: 0 0 0 0 0 0 0 0 12 0 0 0 0 12 0 % T
% Val: 34 0 12 12 0 0 0 0 12 78 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 67 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _