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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS4L2
All Species:
13.33
Human Site:
S392
Identified Species:
36.67
UniProt:
Q2T9F4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2T9F4
NP_291025
439
48884
S392
V
S
S
A
V
S
P
S
I
I
P
Q
E
D
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092200
963
108141
S602
V
S
S
A
V
S
P
S
I
I
S
Q
E
D
P
Dog
Lupus familis
XP_534000
964
108247
S603
V
S
S
A
V
S
P
S
I
A
P
H
E
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIM8
964
108174
N603
V
S
S
T
V
P
S
N
I
T
P
H
E
D
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417220
941
105375
S616
V
S
S
P
V
S
P
S
I
T
P
H
E
D
P
Frog
Xenopus laevis
Q68F70
969
109237
T604
S
W
I
P
D
V
I
T
E
A
P
P
E
D
P
Zebra Danio
Brachydanio rerio
XP_001923719
978
109163
A611
T
A
S
S
G
V
E
A
S
G
V
G
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623793
916
101959
K567
P
D
F
G
K
E
D
K
T
D
E
E
T
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198975
847
94130
M488
L
S
E
T
G
D
S
M
A
D
R
Q
T
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
42.2
41.7
N.A.
41.7
N.A.
N.A.
N.A.
42.1
37.6
37.2
N.A.
N.A.
24.3
N.A.
32.4
Protein Similarity:
100
N.A.
43.4
42.9
N.A.
42.9
N.A.
N.A.
N.A.
43.8
41.1
41.3
N.A.
N.A.
34.8
N.A.
39.9
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
60
N.A.
N.A.
N.A.
80
26.6
6.6
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
66.6
N.A.
N.A.
N.A.
80
33.3
26.6
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
34
0
0
0
12
12
23
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
12
12
12
0
0
23
0
0
0
67
0
% D
% Glu:
0
0
12
0
0
12
12
0
12
0
12
12
67
12
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
23
0
0
0
0
12
0
12
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% H
% Ile:
0
0
12
0
0
0
12
0
56
23
0
0
0
0
0
% I
% Lys:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% N
% Pro:
12
0
0
23
0
12
45
0
0
0
56
12
0
0
78
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% R
% Ser:
12
67
67
12
0
45
23
45
12
0
12
0
12
0
12
% S
% Thr:
12
0
0
23
0
0
0
12
12
23
0
0
23
0
0
% T
% Val:
56
0
0
0
56
23
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _