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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS4L2
All Species:
26.97
Human Site:
S221
Identified Species:
74.17
UniProt:
Q2T9F4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2T9F4
NP_291025
439
48884
S221
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092200
963
108141
S431
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Dog
Lupus familis
XP_534000
964
108247
S432
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIM8
964
108174
S432
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417220
941
105375
S445
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Frog
Xenopus laevis
Q68F70
969
109237
S433
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Zebra Danio
Brachydanio rerio
XP_001923719
978
109163
S440
I
E
E
V
R
L
Q
S
I
H
V
L
R
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623793
916
101959
A396
I
Q
D
V
R
L
R
A
I
E
S
L
R
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198975
847
94130
A317
I
E
S
V
R
L
N
A
I
H
S
L
R
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
42.2
41.7
N.A.
41.7
N.A.
N.A.
N.A.
42.1
37.6
37.2
N.A.
N.A.
24.3
N.A.
32.4
Protein Similarity:
100
N.A.
43.4
42.9
N.A.
42.9
N.A.
N.A.
N.A.
43.8
41.1
41.3
N.A.
N.A.
34.8
N.A.
39.9
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
100
100
80
N.A.
N.A.
53.3
N.A.
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
100
100
93.3
N.A.
N.A.
93.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
89
78
0
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% H
% Ile:
100
0
0
0
0
0
0
0
100
0
0
0
0
0
100
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
89
0
% K
% Leu:
0
0
0
0
0
100
0
0
0
0
0
34
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
78
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
100
0
12
0
0
0
0
0
100
0
0
% R
% Ser:
0
0
12
0
0
0
0
78
0
0
23
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% T
% Val:
0
0
0
100
0
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _