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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC6L All Species: 12.12
Human Site: S1086 Identified Species: 38.1
UniProt: Q2NKX8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2NKX8 NP_060139.2 1250 141103 S1086 I P S S V N K S M N S R R S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092609 1252 141491 S1090 I P S S V N K S M N S R R S L
Dog Lupus familis XP_549075 1268 143171 S1105 I P D S I N K S V N A R R S L
Cat Felis silvestris
Mouse Mus musculus Q8BHK9 1240 138836 S1080 T P G E V N T S L H S R R S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505482 1393 155753 D1083 I T P P A R P D V D L D R V A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGR3 1451 163208 L1237 N G T L A D E L V E E E G E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41877 1009 116656 E864 L S Q I E K G E A R I Q R K Y
Sea Urchin Strong. purpuratus XP_781405 563 63991 H418 V L K K I C D H P R L L S N R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 78.8 N.A. 73.4 N.A. N.A. 49.9 N.A. N.A. 44.4 N.A. N.A. N.A. 24.7 22.9
Protein Similarity: 100 N.A. 98.4 85.8 N.A. 82.3 N.A. N.A. 63.8 N.A. N.A. 60 N.A. N.A. N.A. 42.7 33.2
P-Site Identity: 100 N.A. 100 73.3 N.A. 60 N.A. N.A. 13.3 N.A. N.A. 0 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 N.A. 100 93.3 N.A. 73.3 N.A. N.A. 26.6 N.A. N.A. 26.6 N.A. N.A. N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 25 0 0 0 13 0 13 0 0 0 13 % A
% Cys: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 0 13 13 13 0 13 0 13 0 0 0 % D
% Glu: 0 0 0 13 13 0 13 13 0 13 13 13 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 13 0 0 0 13 0 0 0 0 0 13 0 0 % G
% His: 0 0 0 0 0 0 0 13 0 13 0 0 0 0 0 % H
% Ile: 50 0 0 13 25 0 0 0 0 0 13 0 0 0 0 % I
% Lys: 0 0 13 13 0 13 38 0 0 0 0 0 0 13 0 % K
% Leu: 13 13 0 13 0 0 0 13 13 0 25 13 0 0 50 % L
% Met: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % M
% Asn: 13 0 0 0 0 50 0 0 0 38 0 0 0 13 0 % N
% Pro: 0 50 13 13 0 0 13 0 13 0 0 0 0 0 0 % P
% Gln: 0 0 13 0 0 0 0 0 0 0 0 13 0 0 0 % Q
% Arg: 0 0 0 0 0 13 0 0 0 25 0 50 75 0 13 % R
% Ser: 0 13 25 38 0 0 0 50 0 0 38 0 13 50 0 % S
% Thr: 13 13 13 0 0 0 13 0 0 0 0 0 0 0 0 % T
% Val: 13 0 0 0 38 0 0 0 38 0 0 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _