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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPRED3
All Species:
8.79
Human Site:
S281
Identified Species:
19.33
UniProt:
Q2MJR0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2MJR0
NP_001035987.1
410
42670
S281
P
P
P
G
P
G
P
S
S
A
P
A
K
A
S
Chimpanzee
Pan troglodytes
XP_001166773
410
42535
S281
P
P
P
G
P
G
P
S
S
A
P
A
K
A
S
Rhesus Macaque
Macaca mulatta
XP_001107519
412
42812
A283
P
P
P
G
P
G
P
A
S
A
P
A
K
A
S
Dog
Lupus familis
XP_855400
429
44705
A300
P
P
P
G
P
G
P
A
P
A
P
A
K
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P6N5
408
42776
T279
P
P
P
G
P
G
P
T
P
A
P
A
K
A
S
Rat
Rattus norvegicus
Q3C2P8
410
46787
P285
N
V
I
K
T
Q
P
P
R
A
K
S
R
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513496
539
60559
C415
I
K
T
Q
P
G
H
C
K
W
R
R
R
R
K
Chicken
Gallus gallus
XP_419341
612
68767
K484
D
I
K
G
A
V
I
K
T
Q
P
V
K
F
K
Frog
Xenopus laevis
NP_001121277
405
45787
F303
C
V
Y
C
Q
E
R
F
N
H
E
E
N
G
R
Zebra Danio
Brachydanio rerio
Q6NYK3
413
46811
F311
C
V
Y
C
R
D
M
F
N
H
E
E
N
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395474
376
41869
E285
H
N
P
R
G
S
C
E
Y
A
P
D
P
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.7
92.3
N.A.
94.3
40
N.A.
29.1
22.8
39.5
37.7
N.A.
N.A.
35.8
N.A.
N.A.
Protein Similarity:
100
97.8
99.5
93.9
N.A.
95.6
54.1
N.A.
39.5
36.5
52.9
51.5
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
13.3
N.A.
13.3
20
0
0
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
20
26.6
6.6
6.6
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
19
0
64
0
46
0
46
0
% A
% Cys:
19
0
0
19
0
0
10
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
10
0
0
19
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
55
10
55
0
0
0
0
0
0
0
10
0
% G
% His:
10
0
0
0
0
0
10
0
0
19
0
0
0
0
0
% H
% Ile:
10
10
10
0
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
10
10
0
0
0
10
10
0
10
0
55
0
19
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
19
0
0
0
19
0
0
% N
% Pro:
46
46
55
0
55
0
55
10
19
0
64
0
10
0
0
% P
% Gln:
0
0
0
10
10
10
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
10
0
10
0
10
10
19
28
37
% R
% Ser:
0
0
0
0
0
10
0
19
28
0
0
10
0
0
46
% S
% Thr:
0
0
10
0
10
0
0
10
10
0
0
0
0
0
0
% T
% Val:
0
28
0
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _