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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC5A9
All Species:
13.64
Human Site:
T257
Identified Species:
33.33
UniProt:
Q2M3M2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M3M2
NP_001011547.2
681
74073
T257
P
N
V
T
V
P
N
T
T
C
H
L
P
R
P
Chimpanzee
Pan troglodytes
XP_001164090
670
73003
T257
P
N
V
T
V
P
N
T
T
C
H
L
P
R
P
Rhesus Macaque
Macaca mulatta
XP_001102263
603
65448
G239
S
L
S
H
A
K
G
G
S
V
L
G
G
Y
L
Dog
Lupus familis
XP_539619
703
75954
T279
P
N
A
T
V
P
N
T
T
C
H
L
P
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDT1
685
75047
T253
P
N
T
T
V
P
N
T
T
C
H
L
P
R
P
Rat
Rattus norvegicus
P53790
665
73048
E253
D
G
N
I
T
V
K
E
E
C
Y
T
P
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505333
661
72904
C250
N
K
T
V
D
P
V
C
Y
T
P
R
Q
D
S
Chicken
Gallus gallus
XP_422460
659
72382
D253
D
A
F
H
L
F
R
D
P
V
T
G
D
I
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8WHP3
657
72206
S254
T
T
C
H
L
P
R
S
D
A
F
H
I
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798065
645
71497
L257
F
H
I
F
R
D
P
L
T
A
D
L
P
W
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
85.6
82.2
N.A.
85.2
54.7
N.A.
56.2
75
N.A.
69.7
N.A.
N.A.
N.A.
N.A.
56
Protein Similarity:
100
95
86.9
87
N.A.
92.4
72.9
N.A.
72.9
85.1
N.A.
82.5
N.A.
N.A.
N.A.
N.A.
72.5
P-Site Identity:
100
100
0
86.6
N.A.
93.3
20
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
6.6
86.6
N.A.
93.3
26.6
N.A.
6.6
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
0
0
20
0
0
0
0
20
% A
% Cys:
0
0
10
0
0
0
0
10
0
50
0
0
0
0
0
% C
% Asp:
20
0
0
0
10
10
0
10
10
0
10
0
10
10
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% E
% Phe:
10
0
10
10
0
10
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
10
0
0
0
0
10
10
0
0
0
20
10
0
0
% G
% His:
0
10
0
30
0
0
0
0
0
0
40
10
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
20
0
0
10
0
0
10
50
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
40
10
0
0
0
40
0
0
0
0
0
0
0
0
% N
% Pro:
40
0
0
0
0
60
10
0
10
0
10
0
60
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
20
0
0
0
0
10
0
50
10
% R
% Ser:
10
0
10
0
0
0
0
10
10
0
0
0
0
0
10
% S
% Thr:
10
10
20
40
10
0
0
40
50
10
10
10
0
0
0
% T
% Val:
0
0
20
10
40
10
10
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _