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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK1S1
All Species:
14.55
Human Site:
T175
Identified Species:
40
UniProt:
Q2M2Z5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M2Z5
NP_001156494.1
673
75111
T175
L
S
M
R
D
F
S
T
E
H
K
S
P
Q
P
Chimpanzee
Pan troglodytes
XP_514545
753
83608
T252
S
S
M
G
D
F
S
T
E
H
K
S
P
Q
P
Rhesus Macaque
Macaca mulatta
XP_001093783
678
75482
T175
S
S
M
G
D
F
S
T
E
H
K
S
P
Q
P
Dog
Lupus familis
XP_848458
684
75824
A176
L
S
I
R
G
F
R
A
E
Q
K
S
P
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UXL4
695
76523
T183
S
S
I
E
D
F
S
T
E
L
K
S
N
Q
P
Rat
Rattus norvegicus
XP_230657
694
76892
T183
S
S
I
E
D
F
S
T
E
Q
K
S
N
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506282
490
54940
R11
G
T
Q
F
Q
D
T
R
E
V
N
P
P
S
I
Chicken
Gallus gallus
Q5ZK13
564
61455
N85
L
R
N
Q
T
F
L
N
E
F
N
E
F
E
A
Frog
Xenopus laevis
A1L2H3
736
82655
P186
D
I
Q
C
L
N
K
P
D
K
I
D
G
N
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
93
74.1
N.A.
64.8
64.5
N.A.
38
31.5
32.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87.9
95.2
82.7
N.A.
75.8
75.7
N.A.
50.5
45.7
49.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
86.6
66.6
N.A.
66.6
66.6
N.A.
13.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
73.3
N.A.
73.3
73.3
N.A.
26.6
33.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
56
12
0
0
12
0
0
12
0
0
0
% D
% Glu:
0
0
0
23
0
0
0
0
89
0
0
12
0
12
0
% E
% Phe:
0
0
0
12
0
78
0
0
0
12
0
0
12
0
0
% F
% Gly:
12
0
0
23
12
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% H
% Ile:
0
12
34
0
0
0
0
0
0
0
12
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
12
0
0
12
67
0
0
0
0
% K
% Leu:
34
0
0
0
12
0
12
0
0
12
0
0
0
0
0
% L
% Met:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
12
0
12
0
0
23
0
23
12
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
12
56
0
67
% P
% Gln:
0
0
23
12
12
0
0
0
0
23
0
0
0
67
0
% Q
% Arg:
0
12
0
23
0
0
12
12
0
0
0
0
0
0
0
% R
% Ser:
45
67
0
0
0
0
56
0
0
0
0
67
0
12
0
% S
% Thr:
0
12
0
0
12
0
12
56
0
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _