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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLK1S1 All Species: 16.97
Human Site: S200 Identified Species: 46.67
UniProt: Q2M2Z5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M2Z5 NP_001156494.1 673 75111 S200 S H R Q T A Q S S N V T D S C
Chimpanzee Pan troglodytes XP_514545 753 83608 S277 S H R Q T A Q S S N V T D S C
Rhesus Macaque Macaca mulatta XP_001093783 678 75482 R200 S H R Q T A Q R S N V T D S C
Dog Lupus familis XP_848458 684 75824 S201 S H R Q P A R S G D V T D S C
Cat Felis silvestris
Mouse Mus musculus Q3UXL4 695 76523 S208 S H Q Q T A Q S S C V T D S C
Rat Rattus norvegicus XP_230657 694 76892 S208 S H Q Q T A Q S S C V T D S C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506282 490 54940 G36 F R D T D L R G Y E K K R L D
Chicken Gallus gallus Q5ZK13 564 61455 R110 E K M V R Y G R E I K S G L S
Frog Xenopus laevis A1L2H3 736 82655 D211 T S V A S S E D G R T H R A Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 93 74.1 N.A. 64.8 64.5 N.A. 38 31.5 32.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.9 95.2 82.7 N.A. 75.8 75.7 N.A. 50.5 45.7 49.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 86.6 86.6 N.A. 0 0 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 6.6 6.6 33.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 67 0 0 0 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 67 % C
% Asp: 0 0 12 0 12 0 0 12 0 12 0 0 67 0 12 % D
% Glu: 12 0 0 0 0 0 12 0 12 12 0 0 0 0 0 % E
% Phe: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 12 12 23 0 0 0 12 0 0 % G
% His: 0 67 0 0 0 0 0 0 0 0 0 12 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 23 12 0 0 0 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 0 0 0 23 0 % L
% Met: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 34 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 23 67 0 0 56 0 0 0 0 0 0 0 12 % Q
% Arg: 0 12 45 0 12 0 23 23 0 12 0 0 23 0 0 % R
% Ser: 67 12 0 0 12 12 0 56 56 0 0 12 0 67 12 % S
% Thr: 12 0 0 12 56 0 0 0 0 0 12 67 0 0 0 % T
% Val: 0 0 12 12 0 0 0 0 0 0 67 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _