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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF423 All Species: 30
Human Site: S375 Identified Species: 66
UniProt: Q2M1K9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M1K9 NP_055884.2 1284 144605 S375 S S A T P D S S A S V E R G S
Chimpanzee Pan troglodytes XP_520629 1284 144557 S375 S S A T P D S S A S V E R G S
Rhesus Macaque Macaca mulatta XP_001082640 1292 145402 S375 S S A T P D S S A S V E R G S
Dog Lupus familis XP_544417 1056 117944 R229 F C D K S F I R L S Y L K R H
Cat Felis silvestris
Mouse Mus musculus Q80TS5 1292 145332 S383 S S A T P D S S A S V E R G S
Rat Rattus norvegicus O08961 1311 147208 T383 S S A T P D S T P D P V L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507176 1315 146321 S362 S S A T P D S S A S A E R G S
Chicken Gallus gallus XP_414103 1284 145511 S372 S S A T P D S S A S V E R G S
Frog Xenopus laevis Q6NUD7 1310 148622 N363 S S T T P D S N L S V D S S T
Zebra Danio Brachydanio rerio A1L1R6 1365 151446 S398 S S A T P D S S A S L E R G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z9R4 1228 134159 F392 C E Y C T M K F G N I A G L F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 97.1 73 N.A. 97.5 95.7 N.A. 86.3 92.5 62.8 77.1 N.A. 22.4 N.A. N.A. N.A.
Protein Similarity: 100 99.9 98 73.6 N.A. 98.4 96.8 N.A. 90.1 96.2 75.8 85.8 N.A. 36.1 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 60 N.A. 93.3 100 53.3 93.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 100 66.6 N.A. 93.3 100 73.3 100 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 73 0 0 0 0 0 64 0 10 10 0 0 0 % A
% Cys: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 82 0 0 0 10 0 10 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 64 0 0 0 % E
% Phe: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 10 73 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 10 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 19 0 10 10 10 10 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 82 0 0 0 10 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 64 10 0 % R
% Ser: 82 82 0 0 10 0 82 64 0 82 0 0 10 10 73 % S
% Thr: 0 0 10 82 10 0 0 10 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 55 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _