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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLEC16A All Species: 19.39
Human Site: S309 Identified Species: 47.41
UniProt: Q2KHT3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2KHT3 NP_056041.1 1053 117715 S309 G G E R P K I S L P V S L Y L
Chimpanzee Pan troglodytes XP_001141543 1053 117666 S309 G G E R P K I S L P V S L Y L
Rhesus Macaque Macaca mulatta XP_001104364 1052 117480 S309 G G E R P K I S L P V S L Y L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q80U30 1036 116214 S309 G G E R P K I S L P V S L Y L
Rat Rattus norvegicus XP_213209 1050 117382 S309 G G E R P K I S L P V S L Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509427 1030 117294 T309 T N D F A L Y T E A I K F F N
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002661217 900 100462 K218 A G V R R F T K P L E S L E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393990 1005 114418 E305 L L C Q N Q E E R K H V S I V
Nematode Worm Caenorhab. elegans P46578 892 100843 K210 I F A I K H T K E Y L S E L I
Sea Urchin Strong. purpuratus XP_001176503 739 84126 D57 Q N D S S V F D F F L E K N M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.3 N.A. N.A. 89.7 90.9 N.A. 74.1 N.A. N.A. 58.1 N.A. N.A. 49.3 32.1 41.9
Protein Similarity: 100 99.9 98.2 N.A. N.A. 92.7 94 N.A. 79.1 N.A. N.A. 66.9 N.A. N.A. 66.1 47.4 53.3
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 0 N.A. N.A. 26.6 N.A. N.A. 0 6.6 0
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 26.6 N.A. N.A. 26.6 N.A. N.A. 20 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 10 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 50 0 0 0 10 10 20 0 10 10 10 10 0 % E
% Phe: 0 10 0 10 0 10 10 0 10 10 0 0 10 10 0 % F
% Gly: 50 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % H
% Ile: 10 0 0 10 0 0 50 0 0 0 10 0 0 10 10 % I
% Lys: 0 0 0 0 10 50 0 20 0 10 0 10 10 0 0 % K
% Leu: 10 10 0 0 0 10 0 0 50 10 20 0 60 10 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 20 0 0 10 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 0 0 0 0 50 0 0 0 10 50 0 0 0 0 0 % P
% Gln: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 60 10 0 0 0 10 0 0 0 0 0 10 % R
% Ser: 0 0 0 10 10 0 0 50 0 0 0 70 10 0 0 % S
% Thr: 10 0 0 0 0 0 20 10 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 10 0 0 0 0 50 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 10 0 0 0 50 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _