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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
22.42
Human Site:
S47
Identified Species:
41.11
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S47
T
V
K
K
M
M
G
S
V
M
K
P
H
L
R
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S47
T
V
K
K
M
M
G
S
V
M
K
P
H
L
R
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S47
T
V
K
K
M
M
G
S
V
V
K
P
H
L
R
Dog
Lupus familis
XP_540093
908
102344
T47
T
V
K
K
M
I
G
T
V
M
K
P
H
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
T47
T
V
K
K
M
I
G
T
V
K
K
P
H
L
R
Rat
Rattus norvegicus
NP_001100187
908
102307
T47
T
V
K
K
M
I
G
T
V
M
K
P
H
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
P35
D
A
M
P
A
E
S
P
P
T
T
M
I
N
R
Chicken
Gallus gallus
XP_419963
941
105105
V47
T
V
K
K
M
I
G
V
V
T
K
P
H
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
Honey Bee
Apis mellifera
XP_001120033
614
70598
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
W34
I
A
V
D
L
A
I
W
L
V
E
S
Q
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
93.3
86.6
N.A.
80
86.6
N.A.
6.6
80
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
6.6
86.6
N.A.
N.A.
N.A.
0
0
N.A.
33.3
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
8
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% H
% Ile:
8
0
0
0
0
31
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
54
54
0
0
0
0
0
8
54
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
8
0
0
0
0
54
0
% L
% Met:
0
0
8
0
54
24
0
0
0
31
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
8
8
0
0
54
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% R
% Ser:
0
0
0
0
0
0
8
24
0
0
0
8
0
0
0
% S
% Thr:
54
0
0
0
0
0
0
24
0
16
8
0
0
0
8
% T
% Val:
0
54
8
0
0
0
0
8
54
16
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _