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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
10
Human Site:
S249
Identified Species:
18.33
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S249
N
E
T
S
C
N
S
S
P
Q
L
L
V
T
K
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S249
N
E
T
S
C
N
S
S
P
Q
L
L
V
T
K
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S249
N
E
T
S
C
N
S
S
P
Q
P
L
V
T
K
Dog
Lupus familis
XP_540093
908
102344
D248
W
S
E
E
S
C
S
D
P
Q
P
L
A
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
S248
W
I
E
D
P
C
Y
S
V
P
Q
S
A
P
K
Rat
Rattus norvegicus
NP_001100187
908
102307
S248
W
T
E
E
P
G
Y
S
V
P
Q
S
A
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
R205
G
S
L
S
P
G
R
R
A
P
R
A
L
T
A
Chicken
Gallus gallus
XP_419963
941
105105
N249
K
E
Q
S
E
H
D
N
N
P
P
L
V
V
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
N120
D
K
G
R
S
R
F
N
H
V
L
K
Q
C
E
Honey Bee
Apis mellifera
XP_001120033
614
70598
N8
M
G
V
K
D
L
W
N
I
L
S
P
L
C
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
E239
Q
F
N
L
V
K
M
E
W
P
I
E
Y
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
D31
R
G
R
R
V
A
V
D
L
S
F
W
V
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
93.3
33.3
N.A.
13.3
13.3
N.A.
13.3
33.3
N.A.
N.A.
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
33.3
N.A.
13.3
13.3
N.A.
20
46.6
N.A.
N.A.
N.A.
33.3
20
N.A.
20
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
0
0
8
24
8
8
% A
% Cys:
0
0
0
0
24
16
0
0
0
0
0
0
0
16
0
% C
% Asp:
8
0
0
8
8
0
8
16
0
0
0
0
0
0
0
% D
% Glu:
0
31
24
16
8
0
0
8
0
0
0
8
0
0
16
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
8
16
8
0
0
16
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
8
0
0
8
0
% I
% Lys:
8
8
0
8
0
8
0
0
0
0
0
8
0
0
54
% K
% Leu:
0
0
8
8
0
8
0
0
8
8
24
39
16
0
0
% L
% Met:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
24
0
8
0
0
24
0
24
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
24
0
0
0
31
39
24
8
0
8
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
31
16
0
8
0
8
% Q
% Arg:
8
0
8
16
0
8
8
8
0
0
8
0
0
0
0
% R
% Ser:
0
16
0
39
16
0
31
39
0
8
8
16
0
0
8
% S
% Thr:
0
8
24
0
0
0
0
0
0
0
0
0
0
39
0
% T
% Val:
0
0
8
0
16
0
8
0
16
8
0
0
39
16
0
% V
% Trp:
24
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _