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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
23.94
Human Site:
S189
Identified Species:
43.89
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S189
Y
T
M
S
S
I
K
S
K
L
G
L
D
R
D
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S189
Y
T
M
S
S
I
K
S
K
L
G
L
D
R
D
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S189
Y
T
M
S
T
I
K
S
K
L
G
L
D
R
D
Dog
Lupus familis
XP_540093
908
102344
S189
Y
T
A
S
S
I
K
S
K
L
G
L
D
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
S189
Y
T
I
S
S
I
K
S
K
L
G
L
D
R
D
Rat
Rattus norvegicus
NP_001100187
908
102307
S189
Y
T
V
S
S
I
K
S
K
L
G
L
D
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
T159
P
G
L
D
A
M
W
T
M
A
A
V
F
H
S
Chicken
Gallus gallus
XP_419963
941
105105
E189
Y
T
M
S
S
I
K
E
K
L
G
C
D
R
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
E74
V
T
P
V
F
V
L
E
G
V
A
P
K
L
K
Honey Bee
Apis mellifera
XP_001120033
614
70598
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
L165
M
D
D
I
E
T
K
L
D
L
D
R
R
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
0
80
N.A.
N.A.
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
33.3
86.6
N.A.
N.A.
N.A.
20
0
N.A.
20
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
0
8
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
8
8
0
0
0
0
8
0
8
0
54
0
47
% D
% Glu:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
0
54
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
8
0
54
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
62
0
54
0
0
0
8
0
8
% K
% Leu:
0
0
8
0
0
0
8
8
0
62
0
47
0
8
8
% L
% Met:
8
0
31
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
8
62
0
% R
% Ser:
0
0
0
54
47
0
0
47
0
0
0
0
0
0
8
% S
% Thr:
0
62
0
0
8
8
0
8
0
0
0
0
0
0
0
% T
% Val:
8
0
8
8
0
8
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _