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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDR2 All Species: 11.82
Human Site: S676 Identified Species: 20
UniProt: Q16832 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16832 NP_001014796.1 855 96736 S676 H E P P N S S S S D V R T V S
Chimpanzee Pan troglodytes Q7YR43 909 100624 A728 G A P G D G Q A A Q G P T I S
Rhesus Macaque Macaca mulatta XP_001118206 855 96702 S676 H E P P N S S S S N V P T V S
Dog Lupus familis XP_536144 849 95798 S670 H E P P S S A S G N V P T V S
Cat Felis silvestris
Mouse Mus musculus Q62371 854 96464 C675 R H E P L S S C S S D A T V S
Rat Rattus norvegicus Q63474 910 101146 S729 G L P G D R E S D Q G P T I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515915 914 101965 A734 S T A S P S S A A S R P A V S
Chicken Gallus gallus Q91987 818 91718 G638 D A V L M A E G N R P A E L T
Frog Xenopus laevis O73798 1358 153845 N1097 L R P D T E S N S G Q P T P S
Zebra Danio Brachydanio rerio XP_684261 892 101731 L714 P E G M I A L L S N A P T V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24488 685 78124 Q513 T E G K S L S Q L E F L Q I A
Honey Bee Apis mellifera XP_392450 898 100991 S714 L T G T L R P S C N L K A L S
Nematode Worm Caenorhab. elegans NP_508572 797 90284 I611 N G D L K S Y I L K N P T I Q
Sea Urchin Strong. purpuratus XP_001202828 913 103393 N727 N C N A N L S N C N K S S I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 99.3 96.4 N.A. 95.9 52.8 N.A. 80.1 27.1 21 74.5 N.A. 24.3 30.2 32.8 39.8
Protein Similarity: 100 66 99.5 97.8 N.A. 97.3 66.1 N.A. 85.8 42.8 34.3 82.6 N.A. 41.9 48.7 52 55
P-Site Identity: 100 20 86.6 66.6 N.A. 46.6 26.6 N.A. 26.6 0 33.3 33.3 N.A. 13.3 13.3 13.3 20
P-Site Similarity: 100 46.6 93.3 86.6 N.A. 46.6 40 N.A. 40 26.6 40 46.6 N.A. 40 40 26.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 8 0 15 8 15 15 0 8 15 15 0 8 % A
% Cys: 0 8 0 0 0 0 0 8 15 0 0 0 0 0 0 % C
% Asp: 8 0 8 8 15 0 0 0 8 8 8 0 0 0 0 % D
% Glu: 0 36 8 0 0 8 15 0 0 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 15 8 22 15 0 8 0 8 8 8 15 0 0 0 0 % G
% His: 22 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 8 0 0 0 0 0 36 0 % I
% Lys: 0 0 0 8 8 0 0 0 0 8 8 8 0 0 0 % K
% Leu: 15 8 0 15 15 15 8 8 15 0 8 8 0 15 0 % L
% Met: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 8 0 22 0 0 15 8 36 8 0 0 0 0 % N
% Pro: 8 0 43 29 8 0 8 0 0 0 8 58 0 8 0 % P
% Gln: 0 0 0 0 0 0 8 8 0 15 8 0 8 0 8 % Q
% Arg: 8 8 0 0 0 15 0 0 0 8 8 8 0 0 0 % R
% Ser: 8 0 0 8 15 43 50 36 36 15 0 8 8 0 79 % S
% Thr: 8 15 0 8 8 0 0 0 0 0 0 0 65 0 8 % T
% Val: 0 0 8 0 0 0 0 0 0 0 22 0 0 43 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _