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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDR2 All Species: 25.15
Human Site: S485 Identified Species: 42.56
UniProt: Q16832 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16832 NP_001014796.1 855 96736 S485 R P D Y Q E P S R L I R K L P
Chimpanzee Pan troglodytes Q7YR43 909 100624 G499 S A P C V P N G S A L L L S N
Rhesus Macaque Macaca mulatta XP_001118206 855 96702 S485 R P D Y Q E P S R L I R K L P
Dog Lupus familis XP_536144 849 95798 S479 R P D Y Q E P S R L I R K L P
Cat Felis silvestris
Mouse Mus musculus Q62371 854 96464 S485 R P D Y Q E P S R L I R K L P
Rat Rattus norvegicus Q63474 910 101146 G500 S A P C V P N G S A L L L S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515915 914 101965 S534 G P D Y Q E P S R L L R R L P
Chicken Gallus gallus Q91987 818 91718 A437 Y V V V G I A A L V C T G L V
Frog Xenopus laevis O73798 1358 153845 R782 K V D Y K W E R T V I S N L Q
Zebra Danio Brachydanio rerio XP_684261 892 101731 S520 G P D Y Q E P S R L V R K L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24488 685 78124 D360 N I N T P S A D K N I Y G N S
Honey Bee Apis mellifera XP_392450 898 100991 T494 E E S V R L D T R P E S T V G
Nematode Worm Caenorhab. elegans NP_508572 797 90284 N453 M A R D N L Q N A L I E K M P
Sea Urchin Strong. purpuratus XP_001202828 913 103393 Y518 H P D D E P Q Y H V I D N M M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 99.3 96.4 N.A. 95.9 52.8 N.A. 80.1 27.1 21 74.5 N.A. 24.3 30.2 32.8 39.8
Protein Similarity: 100 66 99.5 97.8 N.A. 97.3 66.1 N.A. 85.8 42.8 34.3 82.6 N.A. 41.9 48.7 52 55
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 80 6.6 26.6 86.6 N.A. 6.6 6.6 26.6 20
P-Site Similarity: 100 6.6 100 100 N.A. 100 6.6 N.A. 93.3 20 46.6 93.3 N.A. 20 26.6 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 0 0 0 0 15 8 8 15 0 0 0 0 0 % A
% Cys: 0 0 0 15 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 58 15 0 0 8 8 0 0 0 8 0 0 0 % D
% Glu: 8 8 0 0 8 43 8 0 0 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 0 8 0 0 15 0 0 0 0 15 0 8 % G
% His: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 0 0 58 0 0 0 0 % I
% Lys: 8 0 0 0 8 0 0 0 8 0 0 0 43 0 0 % K
% Leu: 0 0 0 0 0 15 0 0 8 50 22 15 15 58 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 15 8 % M
% Asn: 8 0 8 0 8 0 15 8 0 8 0 0 15 8 15 % N
% Pro: 0 50 15 0 8 22 43 0 0 8 0 0 0 0 50 % P
% Gln: 0 0 0 0 43 0 15 0 0 0 0 0 0 0 8 % Q
% Arg: 29 0 8 0 8 0 0 8 50 0 0 43 8 0 0 % R
% Ser: 15 0 8 0 0 8 0 43 15 0 0 15 0 15 8 % S
% Thr: 0 0 0 8 0 0 0 8 8 0 0 8 8 0 0 % T
% Val: 0 15 8 15 15 0 0 0 0 22 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 50 0 0 0 8 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _