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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR2
All Species:
22.42
Human Site:
S469
Identified Species:
37.95
UniProt:
Q16832
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16832
NP_001014796.1
855
96736
S469
P
S
E
Q
G
S
N
S
T
Y
D
R
I
F
P
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
P483
E
P
P
P
Y
Q
E
P
R
P
R
G
N
P
P
Rhesus Macaque
Macaca mulatta
XP_001118206
855
96702
S469
P
S
E
Q
E
S
N
S
T
Y
D
R
I
F
P
Dog
Lupus familis
XP_536144
849
95798
S463
P
S
E
Q
E
S
N
S
T
Y
D
R
I
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62371
854
96464
S469
P
S
E
Q
E
S
N
S
T
Y
D
R
I
F
P
Rat
Rattus norvegicus
Q63474
910
101146
P484
E
P
P
P
Y
Q
E
P
R
P
R
G
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
S518
P
S
E
Q
G
S
N
S
T
Y
D
R
I
F
P
Chicken
Gallus gallus
Q91987
818
91718
K421
T
S
P
D
V
S
N
K
E
N
E
D
S
I
T
Frog
Xenopus laevis
O73798
1358
153845
D766
F
S
D
S
E
R
D
D
I
E
Y
P
F
Y
E
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
S504
P
S
E
Q
E
S
S
S
T
Y
E
R
I
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
M344
L
F
K
R
R
T
I
M
H
Y
G
M
R
N
I
Honey Bee
Apis mellifera
XP_392450
898
100991
S478
T
Y
A
I
V
A
T
S
E
L
K
D
V
N
V
Nematode Worm
Caenorhab. elegans
NP_508572
797
90284
H437
I
D
G
N
T
I
K
H
H
V
S
P
S
T
Y
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
R502
M
T
T
V
P
S
R
R
S
N
P
T
Y
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
99.3
96.4
N.A.
95.9
52.8
N.A.
80.1
27.1
21
74.5
N.A.
24.3
30.2
32.8
39.8
Protein Similarity:
100
66
99.5
97.8
N.A.
97.3
66.1
N.A.
85.8
42.8
34.3
82.6
N.A.
41.9
48.7
52
55
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
0
N.A.
100
20
6.6
80
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
93.3
0
N.A.
100
26.6
26.6
93.3
N.A.
26.6
20
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
0
8
8
0
0
36
15
0
0
0
% D
% Glu:
15
0
43
0
36
0
15
0
15
8
15
0
0
0
8
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
8
43
0
% F
% Gly:
0
0
8
0
15
0
0
0
0
0
8
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
15
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
8
0
8
0
0
0
43
8
15
% I
% Lys:
0
0
8
0
0
0
8
8
0
0
8
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
43
0
0
15
0
0
8
15
0
% N
% Pro:
43
15
22
15
8
0
0
15
0
15
8
15
0
15
50
% P
% Gln:
0
0
0
43
0
15
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
8
8
8
8
15
0
15
43
8
0
0
% R
% Ser:
0
58
0
8
0
58
8
50
8
0
8
0
15
0
0
% S
% Thr:
15
8
8
0
8
8
8
0
43
0
0
8
8
8
15
% T
% Val:
0
0
0
8
15
0
0
0
0
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
15
0
0
0
0
50
8
0
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _