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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TST
All Species:
19.39
Human Site:
T22
Identified Species:
35.56
UniProt:
Q16762
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16762
NP_003303.2
297
33429
T22
W
L
A
E
S
I
R
T
G
K
L
G
P
G
L
Chimpanzee
Pan troglodytes
XP_001159714
297
33424
T22
W
L
A
E
S
I
R
T
G
K
L
G
P
G
L
Rhesus Macaque
Macaca mulatta
XP_001086543
308
34591
T22
W
L
A
E
S
I
R
T
G
K
L
G
P
G
L
Dog
Lupus familis
XP_538396
297
33693
A22
W
L
A
E
S
V
R
A
G
K
L
G
P
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P52196
297
33447
S22
W
L
A
E
S
I
R
S
G
R
L
G
P
S
L
Rat
Rattus norvegicus
P24329
297
33388
S22
W
L
A
E
S
I
R
S
G
K
V
G
P
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517033
297
32917
P23
V
A
E
A
L
K
S
P
G
T
G
Q
R
V
Q
Chicken
Gallus gallus
P25324
289
32268
R20
K
W
L
S
E
A
V
R
A
G
R
V
G
A
G
Frog
Xenopus laevis
NP_001088417
294
33239
E22
W
L
S
A
A
L
K
E
S
Q
A
G
A
A
L
Zebra Danio
Brachydanio rerio
NP_001082815
296
32900
V23
D
A
V
K
S
N
R
V
G
P
N
L
R
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91247
277
30681
E8
M
A
V
D
M
I
V
E
P
K
W
V
V
Q
N
Sea Urchin
Strong. purpuratus
XP_784555
302
33055
Y23
I
L
S
P
Q
T
Q
Y
L
R
V
L
D
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08686
304
34200
R23
V
A
S
E
K
V
H
R
I
V
P
V
D
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.4
91.5
N.A.
90.9
90.9
N.A.
60.9
70
60.6
56.2
N.A.
N.A.
N.A.
22.8
46.6
Protein Similarity:
100
100
95.4
95.9
N.A.
95.6
96.3
N.A.
75.7
83.1
76.4
73.4
N.A.
N.A.
N.A.
39.3
62.2
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
6.6
0
26.6
26.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
0
60
33.3
N.A.
N.A.
N.A.
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
47
16
8
8
0
8
8
0
8
0
8
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
0
16
0
0
% D
% Glu:
0
0
8
54
8
0
0
16
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
62
8
8
54
8
39
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
47
0
0
8
0
0
0
0
8
0
% I
% Lys:
8
0
0
8
8
8
8
0
0
47
0
0
0
0
0
% K
% Leu:
0
62
8
0
8
8
0
0
8
0
39
16
0
0
62
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
8
0
0
0
8
8
8
8
0
47
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
8
0
8
0
8
8
% Q
% Arg:
0
0
0
0
0
0
54
16
0
16
8
0
16
0
0
% R
% Ser:
0
0
24
8
54
0
8
16
8
0
0
0
0
16
0
% S
% Thr:
0
0
0
0
0
8
0
24
0
8
0
0
0
0
16
% T
% Val:
16
0
16
0
0
16
16
8
0
8
16
24
8
8
0
% V
% Trp:
54
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _