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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLPP
All Species:
23.03
Human Site:
Y118
Identified Species:
38.97
UniProt:
Q16740
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16740
NP_006003.1
277
30180
Y118
N
K
K
P
I
H
M
Y
I
N
S
P
G
G
V
Chimpanzee
Pan troglodytes
XP_512312
277
30084
Y118
N
K
K
P
I
H
M
Y
I
N
S
P
G
G
V
Rhesus Macaque
Macaca mulatta
XP_001087805
270
28896
Y118
N
K
K
P
I
H
M
Y
I
N
S
P
G
E
Q
Dog
Lupus familis
XP_854538
273
29694
Y114
N
K
K
P
I
H
M
Y
I
N
S
P
G
G
M
Cat
Felis silvestris
Mouse
Mus musculus
O88696
272
29782
Y114
N
K
K
P
I
H
M
Y
I
N
S
P
G
G
V
Rat
Rattus norvegicus
XP_001055676
333
36190
Y175
N
K
K
P
I
H
M
Y
I
N
S
P
G
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088816
247
27316
G105
P
G
G
S
V
T
A
G
L
A
I
Y
D
T
M
Zebra Danio
Brachydanio rerio
NP_001018520
266
28920
M107
G
P
A
I
Y
D
T
M
Q
Y
I
L
N
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609388
253
27555
M107
G
L
A
I
Y
D
T
M
Q
Y
V
K
P
P
I
Honey Bee
Apis mellifera
XP_392540
237
26294
G96
P
G
G
S
V
T
A
G
L
G
I
Y
D
T
M
Nematode Worm
Caenorhab. elegans
Q27539
221
24247
K80
L
Q
S
E
S
G
K
K
P
I
H
M
Y
I
N
Sea Urchin
Strong. purpuratus
XP_786892
239
26099
G98
H
M
Y
I
N
S
P
G
G
S
V
T
A
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147355
260
28004
T114
A
G
L
A
I
Y
D
T
M
Q
Y
I
R
S
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FN42
241
26265
V100
L
N
S
P
G
G
H
V
T
A
G
L
A
I
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
71.4
90.2
N.A.
85.9
70.2
N.A.
N.A.
N.A.
72.1
71.4
N.A.
56.6
59.2
49
62.4
Protein Similarity:
100
98.9
76.1
91.6
N.A.
88
72.9
N.A.
N.A.
N.A.
79
79.7
N.A.
68.2
69.3
61.7
73.2
P-Site Identity:
100
100
86.6
93.3
N.A.
100
100
N.A.
N.A.
N.A.
0
0
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
N.A.
N.A.
20
6.6
N.A.
6.6
20
6.6
26.6
Percent
Protein Identity:
N.A.
52.7
N.A.
48.3
N.A.
N.A.
Protein Similarity:
N.A.
66.4
N.A.
64.9
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
8
0
0
15
0
0
15
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
8
0
0
0
0
0
15
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
22
15
0
8
15
0
22
8
8
8
0
43
43
0
% G
% His:
8
0
0
0
0
43
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
22
50
0
0
0
43
8
22
8
0
15
15
% I
% Lys:
0
43
43
0
0
0
8
8
0
0
0
8
0
0
0
% K
% Leu:
15
8
8
0
0
0
0
0
15
0
0
15
0
0
8
% L
% Met:
0
8
0
0
0
0
43
15
8
0
0
8
0
0
22
% M
% Asn:
43
8
0
0
8
0
0
0
0
43
0
0
8
0
8
% N
% Pro:
15
8
0
50
0
0
8
0
8
0
0
43
8
15
8
% P
% Gln:
0
8
0
0
0
0
0
0
15
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
15
15
8
8
0
0
0
8
43
0
0
8
0
% S
% Thr:
0
0
0
0
0
15
15
8
8
0
0
8
0
15
0
% T
% Val:
0
0
0
0
15
0
0
8
0
0
15
0
0
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
15
8
0
43
0
15
8
15
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _