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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLPP
All Species:
18.18
Human Site:
S169
Identified Species:
30.77
UniProt:
Q16740
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16740
NP_006003.1
277
30180
S169
G
T
P
G
M
R
H
S
L
P
N
S
R
I
M
Chimpanzee
Pan troglodytes
XP_512312
277
30084
S169
G
T
P
G
M
R
H
S
L
P
N
S
R
I
M
Rhesus Macaque
Macaca mulatta
XP_001087805
270
28896
R169
S
D
P
G
G
R
A
R
L
P
L
W
E
A
E
Dog
Lupus familis
XP_854538
273
29694
S165
G
T
P
G
M
R
H
S
L
P
N
S
R
I
M
Cat
Felis silvestris
Mouse
Mus musculus
O88696
272
29782
S165
G
S
P
G
M
R
H
S
L
P
N
S
R
I
M
Rat
Rattus norvegicus
XP_001055676
333
36190
S226
G
S
P
G
M
R
H
S
L
P
N
S
R
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088816
247
27316
P156
S
R
I
M
I
H
Q
P
S
G
G
A
R
G
Q
Zebra Danio
Brachydanio rerio
NP_001018520
266
28920
Q158
P
S
G
G
A
R
G
Q
A
T
D
I
A
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609388
253
27555
Q158
P
S
G
G
A
Q
G
Q
A
T
D
I
L
I
H
Honey Bee
Apis mellifera
XP_392540
237
26294
P147
A
R
I
M
T
H
Q
P
S
G
G
V
S
G
Q
Nematode Worm
Caenorhab. elegans
Q27539
221
24247
K131
L
L
L
C
A
G
E
K
G
M
R
S
A
L
P
Sea Urchin
Strong. purpuratus
XP_786892
239
26099
R149
R
H
S
L
P
N
S
R
I
M
V
H
Q
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147355
260
28004
G165
Q
P
S
G
G
A
S
G
Q
A
S
D
I
A
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FN42
241
26265
I151
L
P
N
A
T
V
M
I
H
Q
P
S
G
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
71.4
90.2
N.A.
85.9
70.2
N.A.
N.A.
N.A.
72.1
71.4
N.A.
56.6
59.2
49
62.4
Protein Similarity:
100
98.9
76.1
91.6
N.A.
88
72.9
N.A.
N.A.
N.A.
79
79.7
N.A.
68.2
69.3
61.7
73.2
P-Site Identity:
100
100
33.3
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
6.6
20
N.A.
13.3
0
6.6
0
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
N.A.
N.A.
20
33.3
N.A.
33.3
0
13.3
13.3
Percent
Protein Identity:
N.A.
52.7
N.A.
48.3
N.A.
N.A.
Protein Similarity:
N.A.
66.4
N.A.
64.9
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
22
8
8
0
15
8
0
8
15
15
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
15
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
36
0
15
65
15
8
15
8
8
15
15
0
8
22
0
% G
% His:
0
8
0
0
0
15
36
0
8
0
0
8
0
0
8
% H
% Ile:
0
0
15
0
8
0
0
8
8
0
0
15
8
50
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
15
8
8
8
0
0
0
0
43
0
8
0
8
8
0
% L
% Met:
0
0
0
15
36
0
8
0
0
15
0
0
0
0
36
% M
% Asn:
0
0
8
0
0
8
0
0
0
0
36
0
0
0
0
% N
% Pro:
15
15
43
0
8
0
0
15
0
43
8
0
0
8
8
% P
% Gln:
8
0
0
0
0
8
15
15
8
8
0
0
8
0
22
% Q
% Arg:
8
15
0
0
0
50
0
15
0
0
8
0
43
0
0
% R
% Ser:
15
29
15
0
0
0
15
36
15
0
8
50
8
0
8
% S
% Thr:
0
22
0
0
15
0
0
0
0
15
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _