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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP5
All Species:
21.21
Human Site:
S147
Identified Species:
51.85
UniProt:
Q16690
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16690
NP_004410.3
384
42047
S147
C
V
D
V
K
P
I
S
Q
E
K
I
E
S
E
Chimpanzee
Pan troglodytes
XP_001139535
419
45265
S182
C
V
D
V
K
P
I
S
Q
E
K
I
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001086701
506
54861
S269
C
V
D
V
K
P
I
S
Q
E
K
I
E
N
E
Dog
Lupus familis
XP_544014
382
41852
S147
C
V
D
V
Q
P
I
S
Q
E
K
V
D
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFV3
398
43353
L168
F
C
S
K
T
K
A
L
A
A
I
P
P
P
V
Rat
Rattus norvegicus
O54838
384
42076
S147
C
V
D
A
K
P
I
S
Q
E
K
L
E
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512829
379
42172
P144
E
C
C
V
D
V
K
P
I
S
Q
E
K
S
E
Chicken
Gallus gallus
Q9PW71
375
41034
T145
Y
P
E
F
C
A
K
T
K
T
L
S
S
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997730
368
41363
S140
E
L
C
T
E
T
R
S
V
E
V
S
E
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
Y146
F
K
Q
F
A
Q
Q
Y
P
Q
L
C
E
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.4
74.9
92.9
N.A.
43.7
92.7
N.A.
75.7
46.6
N.A.
53.9
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
100
72
75.4
97.4
N.A.
60
96.8
N.A.
85.9
63.5
N.A.
72.9
N.A.
N.A.
N.A.
33
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
0
80
N.A.
20
0
N.A.
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
0
86.6
N.A.
33.3
20
N.A.
40
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
10
10
0
10
10
0
0
0
0
0
% A
% Cys:
50
20
20
0
10
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
50
0
10
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
20
0
10
0
10
0
0
0
0
60
0
10
60
0
60
% E
% Phe:
20
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
10
0
10
30
0
10
0
% I
% Lys:
0
10
0
10
40
10
20
0
10
0
50
0
10
0
10
% K
% Leu:
0
10
0
0
0
0
0
10
0
0
20
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
0
0
50
0
10
10
0
0
10
10
10
0
% P
% Gln:
0
0
10
0
10
10
10
0
50
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
60
0
10
0
20
10
40
20
% S
% Thr:
0
0
0
10
10
10
0
10
0
10
0
0
0
10
0
% T
% Val:
0
50
0
50
0
10
0
0
10
0
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _