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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NRF1
All Species:
22.12
Human Site:
S257
Identified Species:
60.83
UniProt:
Q16656
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16656
NP_001035199.1
503
53541
S257
E
E
Q
K
Q
R
V
S
W
T
Q
A
L
R
T
Chimpanzee
Pan troglodytes
XP_001155812
522
55655
S257
E
E
Q
K
Q
R
V
S
W
T
Q
A
L
R
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539379
503
53583
S257
E
E
Q
K
Q
R
V
S
W
T
Q
A
L
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU00
503
53538
S257
E
E
Q
K
Q
R
V
S
W
T
Q
A
L
R
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509949
473
50506
S228
K
P
G
W
G
K
E
S
C
K
P
I
W
W
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90X44
514
54690
W259
E
Q
K
Q
R
V
S
W
T
Q
A
L
R
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24312
733
77745
S318
E
D
D
K
Q
K
I
S
W
T
H
A
L
R
K
Honey Bee
Apis mellifera
XP_395295
511
54971
S245
E
D
E
K
Q
K
I
S
W
T
H
A
L
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q04073
459
49239
R215
A
N
V
R
S
D
V
R
S
E
D
E
K
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
N.A.
99.5
N.A.
99.5
N.A.
N.A.
86.8
N.A.
N.A.
90.2
N.A.
35.4
38.7
N.A.
47.3
Protein Similarity:
100
96.3
N.A.
99.5
N.A.
99.5
N.A.
N.A.
89.8
N.A.
N.A.
93
N.A.
49.1
56.3
N.A.
62
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
60
60
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
20
N.A.
N.A.
33.3
N.A.
80
86.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
12
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
23
12
0
0
12
0
0
0
0
12
0
0
0
0
% D
% Glu:
78
45
12
0
0
0
12
0
0
12
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
23
0
0
0
0
12
0
0
12
% I
% Lys:
12
0
12
67
0
34
0
0
0
12
0
0
12
0
23
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
12
67
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
12
% P
% Gln:
0
12
45
12
67
0
0
0
0
12
45
0
0
0
12
% Q
% Arg:
0
0
0
12
12
45
0
12
0
0
0
0
12
78
0
% R
% Ser:
0
0
0
0
12
0
12
78
12
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
12
67
0
0
0
12
45
% T
% Val:
0
0
12
0
0
12
56
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
12
67
0
0
0
12
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _