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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMN1
All Species:
9.09
Human Site:
S175
Identified Species:
18.18
UniProt:
Q16637
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16637
NP_000335.1
294
31849
S175
D
E
S
E
N
S
R
S
P
G
N
K
S
D
N
Chimpanzee
Pan troglodytes
XP_001156488
297
32138
S175
D
E
S
E
N
S
R
S
P
G
N
K
S
D
N
Rhesus Macaque
Macaca mulatta
XP_001103970
294
32278
S175
D
E
S
E
N
S
R
S
P
G
N
K
S
D
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97801
288
31236
R170
D
D
S
E
H
S
S
R
S
L
R
S
K
A
H
Rat
Rattus norvegicus
O35876
289
31175
R171
D
D
S
E
H
S
S
R
S
L
R
S
K
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512480
286
31243
N175
R
S
S
G
S
K
Q
N
R
V
K
S
K
A
S
Chicken
Gallus gallus
NP_989530
264
29188
P169
C
T
K
A
R
F
S
P
K
N
L
R
F
P
I
Frog
Xenopus laevis
NP_001082386
282
31341
P175
R
S
H
Q
S
K
D
P
Q
N
R
E
T
P
K
Zebra Danio
Brachydanio rerio
Q9W6S8
281
30968
H171
Q
K
S
G
H
A
K
H
K
S
K
S
N
F
P
Tiger Blowfish
Takifugu rubipres
NP_001129352
278
30764
A174
T
K
P
Q
K
S
K
A
P
K
K
P
P
P
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021034
207
22893
N112
Q
M
K
D
L
W
L
N
E
E
A
I
A
D
A
Sea Urchin
Strong. purpuratus
XP_781229
375
41606
P188
H
Q
P
H
P
P
P
P
H
P
S
S
M
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
92.5
N.A.
N.A.
81.6
79.9
N.A.
63.2
53.7
52
51.7
47.9
N.A.
N.A.
26.1
36
Protein Similarity:
100
98.9
94.5
N.A.
N.A.
86
86.7
N.A.
73.8
67
63.9
60.8
60.8
N.A.
N.A.
36.7
48
P-Site Identity:
100
100
100
N.A.
N.A.
26.6
26.6
N.A.
6.6
0
0
6.6
13.3
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
100
N.A.
N.A.
46.6
46.6
N.A.
33.3
6.6
26.6
40
40
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
9
0
0
9
0
9
25
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
17
0
9
0
0
9
0
0
0
0
0
0
34
0
% D
% Glu:
0
25
0
42
0
0
0
0
9
9
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
0
% F
% Gly:
0
0
0
17
0
0
0
0
0
25
0
0
0
0
0
% G
% His:
9
0
9
9
25
0
0
9
9
0
0
0
0
0
25
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
0
17
17
0
9
17
17
0
17
9
25
25
25
0
9
% K
% Leu:
0
0
0
0
9
0
9
0
0
17
9
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
25
0
0
17
0
17
25
0
9
0
25
% N
% Pro:
0
0
17
0
9
9
9
25
34
9
0
9
9
25
9
% P
% Gln:
17
9
0
17
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
17
0
0
0
9
0
25
17
9
0
25
9
0
0
0
% R
% Ser:
0
17
59
0
17
50
25
25
17
9
9
42
25
0
9
% S
% Thr:
9
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _