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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC37
All Species:
32.42
Human Site:
Y298
Identified Species:
54.87
UniProt:
Q16543
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16543
NP_008996.1
378
44468
Y298
G
L
D
P
V
E
V
Y
E
S
L
P
E
E
L
Chimpanzee
Pan troglodytes
XP_512370
526
59963
S444
C
V
F
Y
L
A
N
S
N
D
L
P
I
K
D
Rhesus Macaque
Macaca mulatta
XP_001105596
429
49954
Y349
G
L
D
P
V
E
V
Y
E
S
L
P
E
E
L
Dog
Lupus familis
XP_854103
380
44607
Y300
G
L
D
P
V
E
V
Y
E
S
L
P
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61081
379
44575
Y299
G
L
D
P
V
E
V
Y
E
S
L
P
E
E
L
Rat
Rattus norvegicus
Q63692
379
44492
Y299
G
L
D
P
V
E
V
Y
E
S
L
P
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512153
414
48571
Y337
G
L
D
P
V
E
V
Y
E
A
L
P
V
K
L
Chicken
Gallus gallus
O57476
393
45590
Y303
G
L
D
P
V
D
V
Y
E
S
L
P
P
E
L
Frog
Xenopus laevis
NP_001080276
371
43467
Y297
G
L
D
P
V
E
V
Y
E
S
L
P
P
E
L
Zebra Danio
Brachydanio rerio
A7YY97
313
36353
H232
E
T
P
K
D
T
V
H
Q
N
T
P
P
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24276
389
45131
F294
G
L
D
P
A
D
V
F
E
S
L
P
D
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02108
370
42687
F301
G
I
D
P
Q
E
V
F
E
Q
L
P
E
E
M
Sea Urchin
Strong. purpuratus
XP_790817
381
44030
F293
G
L
D
P
A
D
V
F
E
T
L
P
K
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06101
506
58367
F407
E
M
K
K
V
K
V
F
K
T
L
I
P
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
88.1
96.5
N.A.
94.9
94.9
N.A.
73.4
81.6
73.8
34.1
N.A.
50.3
N.A.
40.2
53.8
Protein Similarity:
100
52
88.1
98.1
N.A.
96.8
97.3
N.A.
82.8
89
85.7
52.9
N.A.
70.1
N.A.
63.2
72.4
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
80
86.6
93.3
13.3
N.A.
73.3
N.A.
66.6
66.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
33.3
N.A.
93.3
N.A.
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
8
0
0
0
8
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
79
0
8
22
0
0
0
8
0
0
8
0
8
% D
% Glu:
15
0
0
0
0
58
0
0
79
0
0
0
43
79
0
% E
% Phe:
0
0
8
0
0
0
0
29
0
0
0
0
0
0
0
% F
% Gly:
79
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
0
0
8
15
0
8
0
0
8
0
0
0
8
15
8
% K
% Leu:
0
72
0
0
8
0
0
0
0
0
93
0
0
0
72
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
8
79
0
0
0
0
0
0
0
93
29
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
58
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
8
0
0
0
15
8
0
0
0
0
% T
% Val:
0
8
0
0
65
0
93
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _