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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC37
All Species:
44.85
Human Site:
T19
Identified Species:
75.9
UniProt:
Q16543
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16543
NP_008996.1
378
44468
T19
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Chimpanzee
Pan troglodytes
XP_512370
526
59963
T135
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Rhesus Macaque
Macaca mulatta
XP_001105596
429
49954
T19
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Dog
Lupus familis
XP_854103
380
44607
T19
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61081
379
44575
T19
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Rat
Rattus norvegicus
Q63692
379
44492
T19
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512153
414
48571
T54
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Chicken
Gallus gallus
O57476
393
45590
T19
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Frog
Xenopus laevis
NP_001080276
371
43467
T19
V
S
D
D
E
D
D
T
H
P
N
I
D
T
A
Zebra Danio
Brachydanio rerio
A7YY97
313
36353
Q21
A
S
I
A
S
E
W
Q
L
A
E
A
Q
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24276
389
45131
T19
I
S
D
D
E
D
D
T
H
P
N
I
D
T
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02108
370
42687
T20
V
S
D
D
E
D
D
T
H
P
N
I
D
T
P
Sea Urchin
Strong. purpuratus
XP_790817
381
44030
E42
R
E
E
E
Q
K
K
E
R
K
D
V
E
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06101
506
58367
E20
L
S
D
D
S
D
V
E
V
H
P
N
V
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
88.1
96.5
N.A.
94.9
94.9
N.A.
73.4
81.6
73.8
34.1
N.A.
50.3
N.A.
40.2
53.8
Protein Similarity:
100
52
88.1
98.1
N.A.
96.8
97.3
N.A.
82.8
89
85.7
52.9
N.A.
70.1
N.A.
63.2
72.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
6.6
N.A.
80
N.A.
86.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
93.3
N.A.
93.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
8
0
8
0
0
65
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
86
86
0
86
22
0
0
0
8
0
79
15
0
% D
% Glu:
0
8
8
8
79
8
58
15
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
79
8
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
79
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
0
8
0
0
0
8
8
% K
% Leu:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
79
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
79
8
0
0
0
15
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
8
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
93
0
0
15
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
79
0
0
0
0
0
79
0
% T
% Val:
72
0
0
0
0
0
8
0
8
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _