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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC37
All Species:
44.58
Human Site:
S5
Identified Species:
75.44
UniProt:
Q16543
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16543
NP_008996.1
378
44468
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Chimpanzee
Pan troglodytes
XP_512370
526
59963
S121
Q
G
K
M
V
D
Y
S
V
W
D
H
I
E
V
Rhesus Macaque
Macaca mulatta
XP_001105596
429
49954
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Dog
Lupus familis
XP_854103
380
44607
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61081
379
44575
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Rat
Rattus norvegicus
Q63692
379
44492
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512153
414
48571
S40
P
T
K
M
V
D
Y
S
V
W
D
H
I
E
V
Chicken
Gallus gallus
O57476
393
45590
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Frog
Xenopus laevis
NP_001080276
371
43467
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Zebra Danio
Brachydanio rerio
A7YY97
313
36353
R7
_
M
A
S
L
C
Q
R
Q
Q
H
C
V
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24276
389
45131
S5
_
_
_
M
V
D
Y
S
K
W
K
N
I
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02108
370
42687
S6
_
_
M
P
I
D
Y
S
K
W
K
D
I
E
V
Sea Urchin
Strong. purpuratus
XP_790817
381
44030
R28
T
P
S
L
F
R
W
R
H
Q
A
R
V
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06101
506
58367
S6
_
_
M
A
I
D
Y
S
K
W
D
K
I
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
88.1
96.5
N.A.
94.9
94.9
N.A.
73.4
81.6
73.8
34.1
N.A.
50.3
N.A.
40.2
53.8
Protein Similarity:
100
52
88.1
98.1
N.A.
96.8
97.3
N.A.
82.8
89
85.7
52.9
N.A.
70.1
N.A.
63.2
72.4
P-Site Identity:
100
80
100
100
N.A.
100
100
N.A.
80
100
100
0
N.A.
66.6
N.A.
53.8
6.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
80
100
100
21.4
N.A.
83.3
N.A.
61.5
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.8
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
69.2
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
86
0
0
0
0
72
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
65
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
0
0
0
0
0
86
0
8
% I
% Lys:
0
0
15
0
0
0
0
0
22
0
15
8
0
8
0
% K
% Leu:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
8
15
72
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
8
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
15
0
0
0
8
0
0
8
% R
% Ser:
0
0
8
8
0
0
0
86
0
0
0
0
0
0
0
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
72
0
0
0
65
0
0
0
15
0
72
% V
% Trp:
0
0
0
0
0
0
8
0
0
86
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% Y
% Spaces:
79
72
58
0
0
0
0
0
0
0
0
0
0
0
0
% _