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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC37
All Species:
21.52
Human Site:
S346
Identified Species:
36.41
UniProt:
Q16543
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16543
NP_008996.1
378
44468
S346
S
G
L
W
V
P
N
S
K
A
S
E
A
K
E
Chimpanzee
Pan troglodytes
XP_512370
526
59963
K493
V
F
F
Q
R
P
Q
K
P
P
T
F
S
L
T
Rhesus Macaque
Macaca mulatta
XP_001105596
429
49954
S397
S
G
L
W
V
P
N
S
K
A
S
E
A
K
E
Dog
Lupus familis
XP_854103
380
44607
S348
S
G
L
W
V
P
N
S
K
S
S
E
A
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61081
379
44575
S347
S
G
L
W
V
P
N
S
K
S
G
E
A
K
E
Rat
Rattus norvegicus
Q63692
379
44492
S347
S
G
L
W
V
P
N
S
K
S
G
E
A
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512153
414
48571
A385
S
G
L
W
V
P
N
A
K
P
A
S
S
L
D
Chicken
Gallus gallus
O57476
393
45590
A351
S
G
L
W
V
P
N
A
K
A
A
A
E
G
G
Frog
Xenopus laevis
NP_001080276
371
43467
S345
S
G
L
W
V
P
N
S
K
A
A
D
V
T
E
Zebra Danio
Brachydanio rerio
A7YY97
313
36353
P275
N
V
L
S
S
M
N
P
Q
V
A
E
Y
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24276
389
45131
A342
S
G
L
W
V
P
N
A
A
D
L
E
G
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02108
370
42687
W345
R
C
I
A
S
G
L
W
V
P
G
K
A
D
D
Sea Urchin
Strong. purpuratus
XP_790817
381
44030
G341
S
G
L
W
V
P
G
G
G
E
D
K
E
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06101
506
58367
L467
N
E
K
D
F
Q
S
L
K
D
Q
Y
E
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
88.1
96.5
N.A.
94.9
94.9
N.A.
73.4
81.6
73.8
34.1
N.A.
50.3
N.A.
40.2
53.8
Protein Similarity:
100
52
88.1
98.1
N.A.
96.8
97.3
N.A.
82.8
89
85.7
52.9
N.A.
70.1
N.A.
63.2
72.4
P-Site Identity:
100
6.6
100
86.6
N.A.
86.6
86.6
N.A.
53.3
60
73.3
20
N.A.
53.3
N.A.
6.6
40
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
80
73.3
86.6
40
N.A.
66.6
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
22
8
29
29
8
43
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
15
8
8
0
15
36
% D
% Glu:
0
8
0
0
0
0
0
0
0
8
0
50
22
0
36
% E
% Phe:
0
8
8
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
72
0
0
0
8
8
8
8
0
22
0
8
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
65
0
0
15
0
36
8
% K
% Leu:
0
0
79
0
0
0
8
8
0
0
8
0
0
15
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
79
0
8
8
22
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
8
0
8
0
8
0
0
8
0
% Q
% Arg:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
72
0
0
8
15
0
8
43
0
22
22
8
15
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% T
% Val:
8
8
0
0
72
0
0
0
8
8
0
0
8
0
8
% V
% Trp:
0
0
0
72
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _