KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC37
All Species:
22.73
Human Site:
S140
Identified Species:
38.46
UniProt:
Q16543
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16543
NP_008996.1
378
44468
S140
P
E
K
T
E
E
D
S
E
E
V
R
E
Q
K
Chimpanzee
Pan troglodytes
XP_512370
526
59963
S256
P
E
K
T
E
E
D
S
E
E
V
R
E
Q
K
Rhesus Macaque
Macaca mulatta
XP_001105596
429
49954
S140
A
T
L
M
L
M
A
S
S
P
P
P
P
W
M
Dog
Lupus familis
XP_854103
380
44607
S142
P
E
Q
A
E
E
E
S
E
E
V
R
E
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61081
379
44575
S141
P
E
K
A
E
E
D
S
E
E
A
R
E
Q
K
Rat
Rattus norvegicus
Q63692
379
44492
S141
P
E
K
A
E
E
D
S
E
E
A
R
E
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512153
414
48571
S179
K
P
D
Q
E
E
E
S
E
E
Q
K
E
Q
K
Chicken
Gallus gallus
O57476
393
45590
E146
A
E
E
K
E
E
T
E
E
Q
K
E
Q
K
H
Frog
Xenopus laevis
NP_001080276
371
43467
E140
P
E
N
K
Q
V
T
E
E
E
K
E
Q
K
H
Zebra Danio
Brachydanio rerio
A7YY97
313
36353
P92
I
N
I
T
Q
S
W
P
N
E
S
D
P
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24276
389
45131
N134
A
G
R
K
P
D
E
N
L
S
E
E
E
R
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02108
370
42687
P136
T
E
K
K
P
Q
A
P
K
T
D
E
E
D
T
Sea Urchin
Strong. purpuratus
XP_790817
381
44030
T135
E
K
T
E
E
E
M
T
E
E
E
K
E
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06101
506
58367
L160
T
V
E
A
K
K
K
L
D
E
L
Y
K
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
88.1
96.5
N.A.
94.9
94.9
N.A.
73.4
81.6
73.8
34.1
N.A.
50.3
N.A.
40.2
53.8
Protein Similarity:
100
52
88.1
98.1
N.A.
96.8
97.3
N.A.
82.8
89
85.7
52.9
N.A.
70.1
N.A.
63.2
72.4
P-Site Identity:
100
100
6.6
80
N.A.
86.6
86.6
N.A.
53.3
26.6
26.6
20
N.A.
6.6
N.A.
20
40
P-Site Similarity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
66.6
53.3
46.6
26.6
N.A.
46.6
N.A.
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
29
0
0
15
0
0
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
29
0
8
0
8
8
0
22
0
% D
% Glu:
8
58
15
8
58
58
22
15
65
72
15
29
65
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
36
29
8
8
8
0
8
0
15
15
8
15
65
% K
% Leu:
0
0
8
0
8
0
0
8
8
0
8
0
0
0
0
% L
% Met:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
8
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
43
8
0
0
15
0
0
15
0
8
8
8
15
0
0
% P
% Gln:
0
0
8
8
15
8
0
0
0
8
8
0
15
43
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
36
0
8
0
% R
% Ser:
0
0
0
0
0
8
0
50
8
8
8
0
0
0
0
% S
% Thr:
15
8
8
22
0
0
15
8
0
8
0
0
0
0
8
% T
% Val:
0
8
0
0
0
8
0
0
0
0
22
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _