KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5E
All Species:
25.76
Human Site:
S57
Identified Species:
47.22
UniProt:
Q16537
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16537
NP_006237.1
467
54699
S57
L
L
K
D
V
P
S
S
E
Q
P
E
L
F
L
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
N291
Q
L
K
D
A
T
S
N
E
Q
Q
E
L
F
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_865670
487
56972
S57
L
L
K
D
V
P
S
S
E
Q
P
E
L
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61151
467
54695
S57
L
L
K
D
V
P
T
S
E
Q
P
E
L
F
L
Rat
Rattus norvegicus
NP_001100210
429
50328
S57
L
L
K
D
V
P
T
S
E
Q
P
E
L
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
S57
L
L
K
D
V
A
S
S
E
Q
P
E
L
F
L
Chicken
Gallus gallus
XP_419432
476
55266
Q57
K
D
A
T
S
N
E
Q
Q
D
L
F
C
Q
K
Frog
Xenopus laevis
NP_001083870
467
54661
S57
L
L
K
D
I
P
T
S
E
Q
P
E
L
F
L
Zebra Danio
Brachydanio rerio
NP_919396
468
54570
Q57
L
L
K
D
V
S
A
Q
E
Q
P
E
L
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651569
524
59708
L57
S
S
L
E
Q
E
E
L
F
I
R
K
L
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
V61
L
E
Q
Q
E
L
V
V
K
K
L
E
Q
C
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
T103
S
F
K
D
V
P
N
T
E
K
Q
N
L
F
I
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
G168
K
D
D
K
S
T
S
G
E
D
H
A
H
P
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.8
N.A.
95.8
N.A.
99.7
91.6
N.A.
99.7
76
98.2
90.1
N.A.
67.3
N.A.
N.A.
70.2
Protein Similarity:
100
60.4
N.A.
95.8
N.A.
100
91.8
N.A.
99.7
88.6
99.7
95.3
N.A.
78.6
N.A.
N.A.
81.8
P-Site Identity:
100
60
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
0
86.6
80
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
66.6
N.A.
100
N.A.
100
100
N.A.
93.3
6.6
100
86.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
50
36.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
8
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
16
% C
% Asp:
0
16
8
70
0
0
0
0
0
16
0
0
0
0
0
% D
% Glu:
0
8
0
8
8
8
16
0
77
0
0
70
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
8
0
70
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
16
0
70
8
0
0
0
0
8
16
0
8
0
0
8
% K
% Leu:
62
62
8
0
0
8
0
8
0
0
16
0
77
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
47
0
0
0
0
54
0
0
8
0
% P
% Gln:
8
0
8
8
8
0
0
16
8
62
16
0
8
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% R
% Ser:
16
8
0
0
16
8
39
47
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
16
24
8
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
54
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _