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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5E
All Species:
43.33
Human Site:
S170
Identified Species:
79.44
UniProt:
Q16537
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16537
NP_006237.1
467
54699
S170
E
S
Q
E
F
Q
P
S
I
A
K
K
Y
I
D
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
S404
E
S
P
D
F
Q
P
S
I
A
K
R
Y
I
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_865670
487
56972
S170
E
S
Q
E
F
Q
P
S
I
A
K
K
Y
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61151
467
54695
S170
E
S
Q
E
F
Q
P
S
I
A
K
K
Y
I
D
Rat
Rattus norvegicus
NP_001100210
429
50328
S170
E
S
Q
E
F
Q
P
S
I
A
K
K
Y
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506784
467
54655
S170
E
S
Q
E
F
Q
P
S
I
A
K
K
Y
I
D
Chicken
Gallus gallus
XP_419432
476
55266
S168
E
S
P
D
F
Q
P
S
I
A
K
R
F
I
D
Frog
Xenopus laevis
NP_001083870
467
54661
S170
E
N
Q
E
F
Q
P
S
I
A
K
K
Y
I
D
Zebra Danio
Brachydanio rerio
NP_919396
468
54570
S170
E
S
Q
E
F
Q
P
S
A
A
K
K
Y
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651569
524
59708
T165
E
S
Q
D
F
Q
A
T
I
G
K
R
V
I
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
S167
E
S
P
E
F
Q
P
S
I
A
K
K
Y
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
K221
A
S
P
E
T
D
T
K
L
A
K
R
Y
I
D
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
Q402
E
S
P
D
F
N
H
Q
I
A
K
Q
Y
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.8
N.A.
95.8
N.A.
99.7
91.6
N.A.
99.7
76
98.2
90.1
N.A.
67.3
N.A.
N.A.
70.2
Protein Similarity:
100
60.4
N.A.
95.8
N.A.
100
91.8
N.A.
99.7
88.6
99.7
95.3
N.A.
78.6
N.A.
N.A.
81.8
P-Site Identity:
100
80
N.A.
100
N.A.
100
100
N.A.
100
73.3
93.3
93.3
N.A.
60
N.A.
N.A.
93.3
P-Site Similarity:
100
93.3
N.A.
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
80
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
50
36.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
8
93
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
31
0
8
0
0
0
0
0
0
0
0
100
% D
% Glu:
93
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
93
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
85
0
0
0
0
100
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
100
62
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
39
0
0
0
77
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
62
0
0
85
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
31
0
0
0
% R
% Ser:
0
93
0
0
0
0
0
77
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
85
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _