Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UAP1 All Species: 21.21
Human Site: T464 Identified Species: 33.33
UniProt: Q16222 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16222 NP_003106.3 522 58769 T464 N G K S E T I T A D V N H N L
Chimpanzee Pan troglodytes XP_001174283 522 58736 T464 N G K S E T I T A D V N H N L
Rhesus Macaque Macaca mulatta XP_001118199 522 58639 T464 N G K S E T I T A D V N H N L
Dog Lupus familis XP_849867 522 58787 T464 N G K S E T I T A D V N L N L
Cat Felis silvestris
Mouse Mus musculus Q91YN5 522 58590 T464 N G K S E A I T A D V N H N L
Rat Rattus norvegicus XP_573497 521 58376 A464 G K S E T I T A D V N H N L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509643 385 43006 Q350 Q L Q H H V A Q K K I P C V D
Chicken Gallus gallus XP_415568 501 55961 C462 T E D P P A V C E I S P L V S
Frog Xenopus laevis NP_001091348 523 58611 D464 G V C G A A Q D H A E K N M K
Zebra Danio Brachydanio rerio Q7ZWD4 505 56395 S468 P P A V C E I S P L V S Y F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609032 520 58196 S484 H G E V C E I S P F V T Y A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18493 484 53478 P445 K V T A T E K P I Y L K T I V
Sea Urchin Strong. purpuratus XP_779933 489 55054 V443 H D P D G Y P V T C E V S P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64765 502 55741 F460 W V I A A G G F L T H S V P L
Baker's Yeast Sacchar. cerevisiae P43123 477 53458 K442 E D A G A I V K D G V L V E V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99 96.1 N.A. 93.4 93.3 N.A. 48.4 58.8 73.6 56.7 N.A. 50.3 N.A. 36.4 57.8
Protein Similarity: 100 100 99.2 98.8 N.A. 96.9 96.5 N.A. 61.2 72 85.4 71.8 N.A. 69.7 N.A. 55.3 73.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 0 N.A. 0 0 0 13.3 N.A. 20 N.A. 0 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 13.3 N.A. 13.3 6.6 6.6 33.3 N.A. 46.6 N.A. 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 40 38.3 N.A.
Protein Similarity: N.A. N.A. N.A. 57.2 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 14 20 20 7 7 34 7 0 0 0 7 0 % A
% Cys: 0 0 7 0 14 0 0 7 0 7 0 0 7 0 0 % C
% Asp: 0 14 7 7 0 0 0 7 14 34 0 0 0 0 7 % D
% Glu: 7 7 7 7 34 20 0 0 7 0 14 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 7 0 0 0 7 0 % F
% Gly: 14 40 0 14 7 7 7 0 0 7 0 0 0 0 14 % G
% His: 14 0 0 7 7 0 0 0 7 0 7 7 27 0 0 % H
% Ile: 0 0 7 0 0 14 47 0 7 7 7 0 0 7 0 % I
% Lys: 7 7 34 0 0 0 7 7 7 7 0 14 0 0 14 % K
% Leu: 0 7 0 0 0 0 0 0 7 7 7 7 14 7 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 34 0 0 0 0 0 0 0 0 0 7 34 14 34 0 % N
% Pro: 7 7 7 7 7 0 7 7 14 0 0 14 0 14 0 % P
% Gln: 7 0 7 0 0 0 7 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 34 0 0 0 14 0 0 7 14 7 0 7 % S
% Thr: 7 0 7 0 14 27 7 34 7 7 0 7 7 0 0 % T
% Val: 0 20 0 14 0 7 14 7 0 7 54 7 14 14 14 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 7 0 0 14 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _