Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UAP1 All Species: 27.88
Human Site: T363 Identified Species: 43.81
UniProt: Q16222 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16222 NP_003106.3 522 58769 T363 K K I P Y V D T Q G Q L I K P
Chimpanzee Pan troglodytes XP_001174283 522 58736 T363 K K I P Y V D T Q G Q L I K P
Rhesus Macaque Macaca mulatta XP_001118199 522 58639 T363 K K I P Y V D T Q G H L V K P
Dog Lupus familis XP_849867 522 58787 S363 K K I P Y V D S Q G Q L I K P
Cat Felis silvestris
Mouse Mus musculus Q91YN5 522 58590 S363 K K I P Y V D S Q G Y F I K P
Rat Rattus norvegicus XP_573497 521 58376 S363 K K I P Y V D S Q G H L I K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509643 385 43006 V270 P R F I G F C V Q K G A D C G
Chicken Gallus gallus XP_415568 501 55961 E362 K K V P Y I D E E G N L V K P
Frog Xenopus laevis NP_001091348 523 58611 T363 K K I P Y V D T H G V R I H P
Zebra Danio Brachydanio rerio Q7ZWD4 505 56395 G365 K K V P F V D G E G N L V K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609032 520 58196 N400 K K I P F V D N A G K R L T P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18493 484 53478 E363 K K I S Y V N E Q G T I V K P
Sea Urchin Strong. purpuratus XP_779933 489 55054 G343 K K I P F I D G E G K R I L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64765 502 55741 S379 A N G L E K D S V Y H L A E K
Baker's Yeast Sacchar. cerevisiae P43123 477 53458 S362 K K I P A Y D S V T G K Y T K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99 96.1 N.A. 93.4 93.3 N.A. 48.4 58.8 73.6 56.7 N.A. 50.3 N.A. 36.4 57.8
Protein Similarity: 100 100 99.2 98.8 N.A. 96.9 96.5 N.A. 61.2 72 85.4 71.8 N.A. 69.7 N.A. 55.3 73.1
P-Site Identity: 100 100 86.6 93.3 N.A. 80 86.6 N.A. 6.6 60 73.3 60 N.A. 53.3 N.A. 60 53.3
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 93.3 N.A. 13.3 86.6 73.3 86.6 N.A. 73.3 N.A. 80 80
Percent
Protein Identity: N.A. N.A. N.A. 40 38.3 N.A.
Protein Similarity: N.A. N.A. N.A. 57.2 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 0 0 0 7 0 0 7 7 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 0 0 87 0 0 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 7 0 0 14 20 0 0 0 0 7 0 % E
% Phe: 0 0 7 0 20 7 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 7 0 7 0 0 14 0 80 14 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 7 0 20 0 0 7 0 % H
% Ile: 0 0 74 7 0 14 0 0 0 0 0 7 47 0 0 % I
% Lys: 87 87 0 0 0 7 0 0 0 7 14 7 0 60 14 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 0 54 7 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 7 7 0 0 14 0 0 0 0 % N
% Pro: 7 0 0 80 0 0 0 0 0 0 0 0 0 0 80 % P
% Gln: 0 0 0 0 0 0 0 0 54 0 20 0 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 0 0 20 0 0 0 % R
% Ser: 0 0 0 7 0 0 0 34 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 27 0 7 7 0 0 14 0 % T
% Val: 0 0 14 0 0 67 0 7 14 0 7 0 27 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 60 7 0 0 0 7 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _