Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UAP1 All Species: 22.12
Human Site: S92 Identified Species: 34.76
UniProt: Q16222 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16222 NP_003106.3 522 58769 S92 D Q L Q A W E S E G L F Q I S
Chimpanzee Pan troglodytes XP_001174283 522 58736 S92 D Q L Q A W E S E G L F Q I S
Rhesus Macaque Macaca mulatta XP_001118199 522 58639 S92 D Q L Q A W E S E G L F Q I S
Dog Lupus familis XP_849867 522 58787 S92 D Q L Q A W E S E G L F Q I S
Cat Felis silvestris
Mouse Mus musculus Q91YN5 522 58590 S92 E Q L Q A W E S E G L S Q I S
Rat Rattus norvegicus XP_573497 521 58376 S92 D Q L Q A W E S E G L S Q I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509643 385 43006 E32 L T E P Q R R E L F R E L E A
Chicken Gallus gallus XP_415568 501 55961 D90 A A L Q R W E D E G L H Q I S
Frog Xenopus laevis NP_001091348 523 58611 A92 E H L Q E W K A Q G L M E I S
Zebra Danio Brachydanio rerio Q7ZWD4 505 56395 N94 E T L Q K W E N E G L L Q I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609032 520 58196 D129 E K L D A Y R D E G L L Q I S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18493 484 53478 N91 V I L D G L W N K G M D A I G
Sea Urchin Strong. purpuratus XP_779933 489 55054 K91 K N L D R W Y K D G L K Q I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64765 502 55741 K114 E D R E K W W K M G L K A I Y
Baker's Yeast Sacchar. cerevisiae P43123 477 53458 R93 K K E N E Y W R L G L E A I G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99 96.1 N.A. 93.4 93.3 N.A. 48.4 58.8 73.6 56.7 N.A. 50.3 N.A. 36.4 57.8
Protein Similarity: 100 100 99.2 98.8 N.A. 96.9 96.5 N.A. 61.2 72 85.4 71.8 N.A. 69.7 N.A. 55.3 73.1
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 0 66.6 46.6 66.6 N.A. 53.3 N.A. 20 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 6.6 66.6 80 80 N.A. 73.3 N.A. 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. 40 38.3 N.A.
Protein Similarity: N.A. N.A. N.A. 57.2 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 47 0 0 7 0 0 0 0 20 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 7 0 20 0 0 0 14 7 0 0 7 0 0 0 % D
% Glu: 34 0 14 7 14 0 54 7 60 0 0 14 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 27 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 94 0 0 0 0 14 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 94 0 % I
% Lys: 14 14 0 0 14 0 7 14 7 0 0 14 0 0 0 % K
% Leu: 7 0 80 0 0 7 0 0 14 0 87 14 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 7 7 0 0 0 % M
% Asn: 0 7 0 7 0 0 0 14 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 40 0 60 7 0 0 0 7 0 0 0 67 0 0 % Q
% Arg: 0 0 7 0 14 7 14 7 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 40 0 0 0 14 0 0 74 % S
% Thr: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 74 20 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 14 7 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _